Results 151 to 160 of about 269,150 (267)

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Quantifying coupling and causality in dynamic bivariate systems: a unified framework for time-domain, spectral, and information-theoretic analysis. [PDF]

Front Netw Physiol
Sparacino L, Pinto H, Barà C, Antonacci Y, Pernice R, Rocha AP, Faes L.   +6 more
europepmc   +1 more source

A Supramolecular Ferroelectric With Two Sublattices and Polarization Dependent Conductivity

Advanced Science, EarlyView.
Ferroelectric behavior in a supramolecular material with two, independently switchable, sublattices is demonstrated. The sublattices can be associated with the two dipolar groups in the compound. Moreover, the polarization is found to couple to the charge transport in the material, giving rise to a switchable, directional conductivity.
H. Mager, M. Litterst, Sophia Klubertz, Shyamkumar V. Haridas, Oleksandr Shyshov, M. von Delius, M. Kemerink   +6 more
wiley   +1 more source

Functional Connectivity Between Human Motor and Somatosensory Areas During a Multifinger Tapping Task: A Proof-of-Concept Study. [PDF]

NeuroSci
García-Leal R, Prieto-Montalvo J, Guzman de Villoria J, Zanin M, Rausell E.   +4 more
europepmc   +1 more source

Advancing Dry Electroencephalography With Scalable, Soft, and Transcranial Magnetic Stimulation‐Compatible Ti3C2Tx MXene Electrodes for Research and Clinical‐Grade Applications

Advanced Science, EarlyView.
Dry soft Ti3C2Tx MXene electroencephalography (EEG) electrodes provide low impedance (2.1 ± 1.8 kΩ at 10 Hz), long‐term stability, and enable safe simultaneous EEG and transcranial magnetic stimulation (TMS). Across scalp sites, hair types, and recording paradigms, including steady state visual evoked potentials (SSVEP), clinical EEG, and mobile EEG ...
Sneha Shankar, Jakob Michiels, Ksenija Tasich, Ashley Koluda, Ryan Rich, Brian Erickson, Eugenia Angelopoulos, Francesca Cimino, Daryl Hurwitz, Raghav Garg, Spencer R. Averbeck, Doris Xu, Mariam Josyula, Nina Petillo, James J. Gugger, Kathryn A. Davis, John Medaglia, Flavia Vitale   +17 more
wiley   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Comment on "Periodontitis and Oral Cancer" by Xia and Song. [PDF]

Int Dent J
Somay E, Bascil S.
europepmc   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

A narrative review of considerations when assessing potential relationships between Guillain-Barré syndrome and vaccines. [PDF]

Hum Vaccin Immunother
Williams SE, Anastasiou OE, Lino MM, Liang C, Wu J, Hall-Murray C, Chilson E, Dooling K, Hayford K, Begier E.   +9 more
europepmc   +1 more source