Results 41 to 50 of about 1,930,168 (250)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CMS physics technical design report, volume II: Physics performance
, 2007 CMS is a general purpose experiment, designed to study the physics of pp collisions at 14 TeV at the Large Hadron Collider (LHC). It currently involves more than 2000 physicists from more than 150 institutes and 37 countries.
Physics Collaboration +1 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Well-posedness of the microwave heating problem
Discrete and Continuous Models and Applied Computational ScienceA number of initial boundary-value problems of classical mathematical physics is generally represented in the linear operator equation and its well-posedness and causality in a Hilbert space setting was established. If a problem has a unique solution and
Baljinnyam Tsangia
doaj +1 more source
Current theories on El Niño-Southern Oscillation: A review [PDF]
Geofísica Internacional, 2003 The current state of knowledge on the physics of the El Niño-Southern Oscillation (ENSO) phenomenon is presented. The main observed features are described, and the basic physics that control the phenomenon are discussed with results from models of ...
Julio Sheinbaum
doaj
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
An action-related theory of causality [PDF]
, 2005 The paper begins with a discussion of Russell?s view that the notion of cause is unnecessary for science, and can therefore be eliminated. It is argued that this is true for theoretical physics, but untrue for medicine where the notion of cause plays a ...
Gillies, D
core
Materia i przyczynowość - konkrety czy uniwersalia?
Zagadnienia Filozoficzne w Nauce, 2011 Humean doctrine on causality is well known. Since all our knowledge comes from experience, we are able to know that “B follows A” (B propter A) but not that “B is caused by A” (B propter A). All the rest comes from our mental habits.
Michał Heller
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source