Results 91 to 100 of about 345,873 (258)

Formas descentralizadas de resolução de conflitos no direito brasileiro [PDF]

open access: yes, 1999
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Jurídicas.Esta dissertação aborda sobre as principais formas acentuadamente descentralizadas de resoluções de conflitos no Direito brasileiro, incluindo os juizados ...
Canzi, Idir
core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Nota editorial: reflexiones a propósito de la mortalidad infantil

open access: yesRevista de la Facultad de Medicina, 1933
Es un hecho innegable que de diez años a esta parte. las instituciones encargadas de proteger y de velar ,por la salud del niño, han sufrido en Colombia un marcado progreso y una extensa difusión.
Jorge Bejarano
doaj  

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini   +12 more
wiley   +1 more source

Causas de inimputabilidad

open access: yes, 1947
Causas de ...
Rendón G., Gustavo
core   +2 more sources

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Mobbing entre enfermeiros: um estudo empírico [Mobbing among nurses: an empirical study] [Mobbing entre los enfermeros: un estudio empírico]

open access: yesRevista Enfermagem UERJ, 2017
Objetivo: avaliar a existência de condutas de mobbing nos enfermeiros de um hospital da Região Centro de Portugal. Método: estudo descritivo de abordagem quantitativa, correlacional e de natureza transversal.
Andrea Silva Pinto   +1 more
doaj  

Causas de las discapacidades [PDF]

open access: yes, 2011
En este documento se ofrece información sobre las causas de las deficiencias, clasificadas de acuerdo con la siguiente categorización: congénito; problemas en el parto; accidente de tráfico; accidente doméstico; accidente de ocio; accidente laboral; otro
Huete García, Agustín   +1 more
core  

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