Results 91 to 100 of about 736,528 (287)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Cogent Arts & HumanitiesPentecostalism in Africa, particularly in Nigeria, has brought a new chapter in the history of Christianity. However, one of the conspicuous peculiarities of the kind of Pentecostalism that has emerged, especially in Nigeria, is the spiritual warfare and
Babatunde Aderemi Adedibu +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
ACE’s Contextualization for Healthcare Workers [PDF]
, 2018 There is a well-established causative relationship between Adverse Childhood Experiences (ACE’s) and pathology. Despite strong supporting evidence, some healthcare workers are unaware of how deep this relationship is.
Konstantinopoulos, Nektarios
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
On Japanese Causative: Review of Shibatani's Notion of Causative
Kansas Working Papers in Linguistics, 1990 In this article, characteristics of Japanese causative constructions are reviewed and discussed based on an article by Masayoshi Shibatani (1976), who has worked extensively in Japanese causative.
Shimada, Misaki
doaj +1 more source
The Diversity of Causative Agent Associated with Bacterial Diseases on Catfish (Clarias gariepinus) with Molecular Based from Kendal, Indonesia [PDF]
Bacterial disease is still a big concern in intensive catfish culture in Indonesia. The aim of this research was to find out causative agent on cat fish based on the 16S rDNA gene sequences.
Aryati, Restiana Wisnu +3 more
core
Distinguishing Infections on Different Graph Topologies [PDF]
, 2013 The history of infections and epidemics holds famous examples where understanding, containing and ultimately treating an outbreak began with understanding its mode of spread.
Caramanis, Constantine +3 more
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source