Results 81 to 90 of about 736,528 (287)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Questions on transitivity [PDF]
, 2010 This handout (it isn’t a paper) presents phenomena and questions, rather than conclusions, related to the concept of transitivity. The idea is to return to these questions at the end of the Workshop to see if we can have a clearer consensus about the ...
LaPolla, Randy J.
core
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Semantic maps as metrics on meanings
Linguistic Discovery, 2010 By using the world?s linguistic diversity, the study of meaning can be transformed from an introspective inquiry into a subject of empirical investigation.
Michael Cysouw
doaj +1 more source
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Semantic maps and word formation: Agents, Instruments, and related semantic roles
Linguistic Discovery, 2010 The semantic map methodology has been applied mainly to the analysis of the multifunctionality of grammatical morphemes?they allow one to deal with this problem without having to decide between monosemic and polysemic analyses.
Eugenio R. Luján
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Le corpus multilingue InterCorp : nouveaux paradigmes de recherche en linguistique contrastive et en traductologie [PDF]
Studii de Lingvistica, 2017 Linguistic corpora have changed the research paradigm in many linguistic disciplines, allowing researchers to exploit large data based on real occurrences in authentic contexts.
Olga Nádvorníková
doaj