Results 131 to 140 of about 1,967,307 (350)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The effect of phenotypic aging on the relationship between cancer history and mortality in US adults

Frontiers in Aging
Cancer survivors may have an accelerated biological aging process compared to cancer-free individuals. In this study, we aimed to investigate associations between clinical measures of biological aging and mortality (all-cause, cancer, and cardiovascular ...
Meng-Hua Tao, Meng-Hua Tao, Chun-Hui Lin, Shu-Chun Chuang, Wan-Ting Su, Wan-Ting Su, Horng-Shiuann Wu   +6 more
doaj   +1 more source

Functional mobility and 10-year all-cause and cause-specific mortality in older people from São Paulo, Brazil

, 2022
Carla Ferreira do Nascimento, Alejandra Andrea Roman Lay, Yeda A. O. Duarte, Alexandre Dias Porto Chiavegatto Filho   +3 more
openalex   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Association between dietary flavonol intake and mortality risk in the U.S. adults from NHANES database

Scientific Reports
Using updated National Health and Nutrition Examination Survey (NHANES) follow-up data, and a large nationwide representative sample of adult U.S. citizens, the aim of this study was to explore the relationship between dietary flavonol intake, all-cause ...
Zhiqiang Zong, Xiang Cheng, Yang Yang, Jianchao Qiao, Jiqing Hao, Fanfan Li   +5 more
doaj   +1 more source

Being Born Under Adverse Economic Conditions Leads to a Higher Cardiovascular Mortality Rate Later in Life: Evidence Based on Individuals Born at Different Stages of the Business Cycle [PDF]

We connect the recent medical and economic literatures on the long-run effects of early-life conditions, by analyzing the effects of economic conditions on the individual cardiovascular (CV) mortality rate later in life, using individual data records ...
Christensen, Kaare, Doblhammer-Reiter, Gabriele, van den Berg, Gerard J.   +2 more
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Causes of death and trends in mortality from the year 2000 to 2017 in patients with acute myocardial infarction

Annals of Medicine
Objective To investigate the most common causes of death and trends in cause-specific long-term mortality in patients hospitalized for acute myocardial infarction (AMI).Methods This analysis was based on 10,718 patients, aged 25–74 years, recorded by the
David Scharlach, Timo Schmitz, Philip Raake, Jakob Linseisen, Christa Meisinger   +4 more
doaj   +1 more source

Do Childhood Vaccines Have Non-Specific Effects on Mortality [PDF]

, 2003
A recent article by Kristensen et al. suggested that measles vaccine and bacille Calmette–Guérin (BCG) vaccine might\ud reduce mortality beyond what is expected simply from protection against measles and tuberculosis.
Boyce , G. Thomas, Cooper, O. William, Griffin, R. Martin, Wright, F. Peter   +3 more
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source