Results 201 to 210 of about 4,353,386 (346)

Cause of death statistics in 2022 in the Republic of Korea. [PDF]

Ewha Med J
Oh JH, Seo J, Park HJ.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Análise da concordância da codificação de causa básica de óbito por acidentes de trânsito

Revista de Saúde Pública
OBJETIVO: Avaliar a concordância de informações pesquisadas sobre causa básica de óbito por acidente de trânsito e compará-las com as codificações feitas a partir das Declarações de Óbitos.
Roberto M. Ladeira, Mark D. C. Guimarães   +1 more
doaj  

Cause of death for patients who present with primary progressive apraxia of speech. [PDF]

Parkinsonism Relat Disord
Utianski RL, Meade G, Duffy JR, Boland S, Whitwell JL, Botha H, Josephs KA.   +6 more
europepmc   +1 more source

Coccidioidomycosis: An underreported cause of death—Arizona, 2008–2013 [PDF]

, 2017
Jefferson M. Jones, Lia Koski, Mohammed A. Khan, Shane Brady, Rebecca Sunenshine, Ken Komatsu   +5 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Causas básicas e associadas de morte por Aids, Estado de São Paulo, Brasil, 1998

Revista de Saúde Pública
OBJETIVOS: Descrever o padrão da mortalidade devida a Aids segundo causas básica e associadas de morte no Estado de São Paulo, em 1998. MÉTODOS: Os dados sobre a mortalidade e a população residente no Estado de São Paulo, SP, para 1998, foram obtidos na ...
Augusto Hasiak Santo, Celso Escobar Pinheiro, Margarete Silva Jordani   +2 more
doaj  

Correction: Cause of death coding in asthma. [PDF]

BMC Med Res Methodol
Chung A, Opoku-Pare GA, Tibble H.
europepmc   +1 more source

Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) study: Causes of death and associated factors over a decade of follow-up in a cohort of HIV-infected adults in rural Tanzania

, 2021
Getrud Joseph Mollel, Lilian Moshi, Hoda Hazem, Anna Eichenberger, Olivia Kitau, Herry Mapesi, Tracy R. Glass, Daniel H. Paris, Maja Weisser, Fiona Vanobberghen   +9 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source