Results 241 to 250 of about 4,353,386 (346)

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Determining the cause of death through mortality surveillance using verbal autopsy in Karachi, Pakistan. [PDF]

J Glob Health
Allana R, Yildirim I, Ariff S, Belgaumi SM, Ahsan N, Aguolu O, Umair S, Ali SA, Maqsood T, Iqbal M, Malik FA, Omer SB, Kazi AM.   +12 more
europepmc   +1 more source

The Importance of Accurately Determining the Underlying Cause of Death in a Causal Chain Situation. Effects on Legal Liability. Essential Role of Forensic Investigation in Determining the Underlying Cause [PDF]

Claudiu-Gabriel Galu
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

A retrospective and comprehensive analysis of excess life-years lost, mortality risk, and cause of death among severe mental illness in China. [PDF]

BMC Med
Fang X, Yu H, Wu C, Tan J, Sun F, Qian N, Zhou H, Zhou J, Zhang X.   +8 more
europepmc   +1 more source

Causes of Death [PDF]

Nature, 1968
openaire   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Preserving Trial Endpoint Specificity and Cause of Death Attribution in Cardiovascular Trials: Insights From MARINER. [PDF]

JACC Adv
Hogan SE, Canonico ME, King RW, Low Wang CC, Nehler MR, Parr J, Rogers RK, Lu W, Albanese J, Barnathan ES, Spyropoulos AC, Douketis JD, Bonaca MP, Capell WH.   +13 more
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Premature Mortality in Patients With Anorexia Nervosa: A Matched Cohort Study of Cause of Death. [PDF]

Int J Eat Disord
Auger N, Israël M, Steiger H, Low N, Chadi N, Brousseau É, Ayoub A, Côté-Corriveau G.   +7 more
europepmc   +1 more source