Results 251 to 260 of about 4,353,386 (346)

Two cases of driver death caused by airbag rupture [PDF]

Qifeng Miao, Xinzhe Chen, Fengchong Lan, Xuan Zhao, Weicheng Zhang, Meichao Zhang, Dawei Liu, Zhenzhu Song, Dongliang Liu, Weidong Zhao, Dong‐Ri Li   +10 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Cause of Death Analysis in a 9½-Year-Old with COVID-19 and Dravet Syndrome. [PDF]

Pathophysiology
Meher VR, Huntsman RJ, Green FHY, Wooff JC, Auer RN.   +4 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Accuracy of information on the underlying cause of death: An analysis in Colombia during the COVID-19 pandemic in 2021. [PDF]

PLoS One
Chaparro-Narváez P, Manrique Sanchez JA, Berrio-Parra L, Urrego Ricaurte DC, Torres-Rojas LJ, Orjuela Cantor NP, Mora Aguirre CP, Quevedo YR, Suárez C, Castañeda-Orjuela C.   +9 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Forensic Point-of-Care Test to Unveil the Cause of Death in Sudden Cardiac Deaths: A Case Series. [PDF]

Cureus
Js S, Vijayakumar S, Alikkal S, Arora A.
europepmc   +1 more source

Multiple Cause of Death, 1988

, 1988
United States Department Of Health And Human Services. National Center For Health Statistics
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source