Results 71 to 80 of about 5,176,576 (252)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Causes of Death of the Population in Latvia, 1919-1939
, 2021 This dataset contains data on causes of death of the population in Latvia in 1919-1939. Dataset "Causes of Death of the Population in Latvia, 1919-1939" was published implementing project "Historical Sociology of Modern Restorations: a Cross-Time ...
Markevičiūtė, Jurgita +4 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Causes of Death of the Population in Estonia, 1919-1939
, 2021 This dataset contains data on causes of death of the population in Estonia in 1919-1939. Dataset "Causes of Death of the Population in Estonia, 1919-1939" was published implementing project "Historical Sociology of Modern Restorations: a Cross-Time ...
Markevičiūtė, Jurgita +4 more
core +1 more source
Regional Sea Level Changes in the East China Sea from 1993 to 2020 Based on Satellite Altimetry
Journal of Marine Science and EngineeringA comprehensive analysis was carried out to investigate the driving factors and influencing mechanisms of spatiotemporal variation of sea level at multiple scales in the East China Sea (ECS) via satellite altimetry datasets from 1993 to 2020.
Lujie Xiong, Fengwei Wang, Yanping Jiao
doaj +1 more source
The main causes of sore throat and prospects for antimicrobial therapy
Медицинский совет, 2015 Sore throat is the most common complaint of patients presenting to various clinical specialists. The most common causes of sore throat are infectious agents.
A. I. Kryukov +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Polycystic Ovary Syndrome (PCOS): Symptoms, Causes, and Treatment
Clinical and Experimental Obstetrics & GynecologyObjective: The review aims to provide an overview of the pathogenesis, clinical manifestations, and treatment methods of polycystic ovary syndrome (PCOS). Mechanism: The etiology of PCOS is multifaceted, intricately intertwined with genetic determinants,
Hai Bai, Huanhuan Ding, Mingming Wang
doaj +1 more source
Scientia et Fides, 2014 Según Aristóteles existe una relación intrínseca entre lenguaje ordinario, lógica y ontología, la cual es un elemento fundamental para el conocimiento de la realidad.
Miguel Martí Sánchez
doaj +1 more source