Results 211 to 220 of about 165,358,789 (245)

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source

Prophylactic implantation of implantable cardioverter-defibrillator for the primary prevention of sudden cardiac death after myocardial infarction: protocol for systematic review and meta-analysis of randomised controlled trials. [PDF]

BMJ Open
Amarasekera AT, Gunaratne AW, Kovoor JG, Thiagalingam A, Chow C, Zaman S, Sivagangabalan G, Tung MKY, Stiles M, Crozier I, Koh KT, Sticherling C, Reichlin T, Wranicz JK, Avramides D, Tsioufis K, Ritter O, Bode K, Tovia-Brodie O, Chia K, Park RE, Nentwich K, Michowitz Y, Svetlosak M, Hatala R, Zabel M, Nagy VK, Merkely B, Taylor A, Billot L, Kovoor P, PROTECT-ICD Study Investigators.   +31 more
europepmc   +1 more source

Controllable Cascade Aggregation Ion Programmed Nanomachines and Simple Isolation Enable Tumor‐Derived Small Extracellular Vesicles Detection for Enhanced Breast Cancer Assessment

Advanced Science, EarlyView.
This study developed a convenient, enzyme‐free detection platform based on controllable aggregation ion nanomachines. Its favorable anti‐interference capacity and high sensitivity meet the detection requirements for clinical samples processed via a simple filtration method within 10 min.
Zhihao Zhang, Zijing Liu, Xiangyue Meng, Pengjun Jiang, Jie Qu, Yu Jiang, Binxu Qiu, Jie Chen, Piaopiao Chen   +8 more
wiley   +1 more source

Temporal Trends and Predictors of Mortality in Heart Failure with Reduced Ejection Fraction: The Role of Renal Function and Left Ventricular Improvement. [PDF]

J Clin Med
Lopez-Lopez A, Rivas Vázquez E, Regueiro-Abel M, Álvarez-Suárez CC, Abou Johk-Casas C, Elices-Teja J, Ríos Vázquez R, Santamarina-Pernas G, González-Juanatey C.   +8 more
europepmc   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han, Guolin Miao, Yinqi Zhao, Zhiyong Du, Kaikai Lu, Changqi Xiao, Aiden Xian, Jiaxin Duanmu, Zihao Zhou, Jinxuan Chen, Lianxin Zhang, Chao Zhai, Yitong Xu, Zhaoling Li, Xianqin Shen, Sijing Shi, Jingxuan Chen, Si Mei, Yuan Fang, Liwen Zheng, Ling Zhang, Yuhui Wang, Wei Huang, Erdan Dong, Xunde Xian   +24 more
wiley   +1 more source

Evaluation of Computer-aided Detection for Identifying Missed Gastric Cancer After Endoscopic Submucosal Dissection. [PDF]

DEN Open
Minamide T, Sato T, Sakaguchi S, Kawata N, Maeda Y, Yoshida M, Yamamoto Y, Okumura T, Suwa T, Ashizawa H, Shigeta K, Nakamura H, Notsu A, Uraoka T, Ono H.   +14 more
europepmc   +1 more source

Assessing implementation of the Maternal Death Surveillance and Response (MDSR) framework in North Aceh District, Indonesia: a qualitative study. [PDF]

BMC Public Health
Sufri S, Jannah M.
europepmc   +1 more source

Cardiorenal Protection in Type 2 Diabetes: A Systematic Review Comparing Glucagon-Like Peptide-1 Receptor Agonists and Sodium-Glucose Cotransporter-2 Inhibitors. [PDF]

Cureus
Branigan P, Duong VNY, Branigan S.
europepmc   +1 more source

Hidden toll of violent deaths during pregnancy and the postpartum period: a nationwide analysis of Mexican death records. [PDF]

BMJ Public Health
Gazeley U, Gargiulo M, Eilerts-Spinelli H, Hassan A, Díaz-Juárez I, Palfreyman A.   +5 more
europepmc   +1 more source

Clinicopathological, multimodal treatment, and survival patterns for men with breast cancer in England and Wales: a population-based cohort study. [PDF]

EClinicalMedicine
Boyle JM, Withrow D, Blacker S, Wang L, Delon C, Medina J, Dodwell D, Verrill M, Horgan K, Cromwell DA.   +9 more
europepmc   +1 more source