Results 121 to 130 of about 122,064 (340)

Clinical Spectrum and Management of Caustic Ingestion: A Case Series Presenting Three Opposing Outcomes

open access: yesThe American journal of case reports, 2016
Case series Patient: Fenale, 77 • Female, 46 • Female, 33 Final Diagnosis: Caustic injury Symptoms: — Medication: — Clinical Procedure: Surgery Specialty: Surgery Objective: Unusual clinical course Background: Ingestion of caustic substances is a medical
Antonios I. Vezakis   +7 more
semanticscholar   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

THE NONLINEAR CAUSTIC

open access: yesTamkang Journal of Mathematics, 1991
In this paper the boundary layer at the nonlinear caustic is discussed and a nonlinear Airy equation is,obtained by adapting techniques from linear theory. It is shown that the incident beam undergoes a phase shift by an amount of $\pi/2$ as it passes through the caustic and becomes the outgoing beam.
openaire   +3 more sources

Dual behavior of caustic optical beams facing obstacles

open access: yes, 2017
A full propagation analysis on both fold-type and cusp-type caustic optical beams under various setups of obstructions is theoretically and experimentally performed.
P. Vaveliuk   +3 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

On the class of caustics by reflection

open access: yes, 2013
Given any light position S in the complex projective plane P^2 and any algebraic curve C of P^2 (with any kind of singularities), we consider the incident lines coming from S (i.e.
Josse, Alfrederic, Pene, Francoise
core   +1 more source

Foregut caustic injuries: results of the world society of emergency surgery consensus conference

open access: yesWorld Journal of Emergency Surgery, 2015
IntroductionLesions of the upper digestive tract due to ingestion of caustic agents still represent a major medical and surgical emergency worldwide.
L. Bonavina   +21 more
semanticscholar   +1 more source

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