Results 231 to 240 of about 122,064 (340)

Esophageal Mucosal Injuries From Drugs, Radiation, and Caustic Agents. [PDF]

Korean J Helicobacter Up Gastrointest Res
Bae HJ, Choe Y.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Delayed Management of Esophageal Stricture due to Caustic Ingestion: A Case Report. [PDF]

Gastro Hep Adv
Burhan T, Widodo B, Sugihartono T, Riswanto AY.   +3 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Endoscopic closure of a refractory post-surgical pouch by mucosal resection and suturing. [PDF]

Endoscopy
Sais A, Rivory J, Rostain F, Lupu A, Monneuse O, Grimaldi J, Pioche M.   +6 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Spacetime perspective of gravitational lensing in perturbed cosmologies. [PDF]

Sci Rep
Kling TP, Pooler SM.
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

High magnification optical imaging systems for the characterization of soft X-ray focii. [PDF]

J Synchrotron Radiat
Al Haddad A, Sarracini A, Schnorr K, Knopp G, Krempasky J, Arrell C, Augustin S, Bassement L, Brupbacher K, Vila-Comamala J, David C, Flechsig U, Follath R, Guo Z, Herzog M, Knurr J, Lombosi C, Manetti E, Mandal S, Morillo-Candas AS, Qi P, Sorokin BV, Stubbs S, Sun Z, Tiefenbacher SC, Vonka J, Wagner UH, Xie X, Yang N, Zhang H, Bostedt C.   +30 more
europepmc   +1 more source