Results 111 to 120 of about 3,852 (253)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The discriminant of quasi m-boundary singularities
Demonstratio MathematicaWe describe the discriminant of deformations of simple quasi m-boundary equivalence classes for m≥2m\ge 2. All quasi simple mm-boundary classes are right equivalent to Arnold’s singularities (ADE).
Alharbi Fawaz, Al-hudhali Eman
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Wave Fronts and Caustics of Vector Fields.
, 2002 : We consider singularities of the wave front of a smooth plane curve from the viewpoint of planar vector fields and their singularities. This approach allows giving complete description of wave fronts, caustics, and their singularities in ...
Varin V. P. http://library.keldysh.ru/author_page.asp?aid=2304
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Catastrophe Theory and Caustics [PDF]
SIAM Review, 1983 In this paper it is shown by elementary methods that in codimension two and under the assumption that light rays are straight lines, a caustic is the catastrophe set for a timefunction. The general case is also discussed.
openaire +1 more source
Random caustics and intensity fluctuations in weakly disordered media
, 2012 Random caustics are a ubiquitous phenomenon of ray or particle propagation through weakly disordered media. They lead to a pronounced branching not only of the ray or particle flow density but also in the intensity of corresponding wave flows.
Fleischmann, R. +5 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Caustic stenosis of the esophagus and malignant neoplasia: A dilemma
Frontiers in Oncology, 2022 Nelson Adami Andreollo +4 more
doaj +1 more source