Effects of vatinoxan on gastrointestinal motility, sedation, and antinociception during and after long-lasting detomidine infusion in horses. [PDF]
Abstract Background Sedation in horses is typically achieved using alpha‐2 adrenoceptor agonists, although their use is associated with multiple side effects. A peripheral alpha‐2 adrenoceptor antagonist, vatinoxan, can alleviate many of these. Objectives To evaluate the effects of vatinoxan infusion on gastrointestinal motility, sedation, and ...
Obrochta B +7 more
europepmc +2 more sources
Osseous pathologic changes in the thoracic region of the equine vertebral column: A descriptive post-mortem study in three breeds. [PDF]
Abstract Background Data on equine thoracic pathology hardly exist in breeds other than Thoroughbreds. Objectives To describe pathological changes of the osseous thoracic vertebral column in Warmblood horses, Shetland ponies and Konik horses, and to compare prevalence and severity. Study design Descriptive post‐mortem study. Methods Computed tomography
Spoormakers TJP +4 more
europepmc +2 more sources
Validation of the Equine Urticaria Activity Score for the assessment of chronic recurrent urticaria in horses. [PDF]
Background – Recurrent urticaria is common in horses. The pathophysiology is poorly understood and treatment options are limited. Often only glucocorticoids are effective for controlling clinical signs, albeit with potential adverse effects. Studies investigating new treatments need a validated objective scoring system for the grading of skin lesions ...
Birkmann K +5 more
europepmc +2 more sources
Should the use of omeprazole be allowed during equestrian competition? [PDF]
Abstract Background Prioritising equine welfare, making evidenced‐based policy, and consistent decision‐making across sports are crucial to maintaining the social licence for equestrian sport. Regulations on the use of omeprazole during competition differ; all regulators argue that their rules prioritise welfare. This discrepancy is a matter of concern
Campbell MLH, Sykes BW.
europepmc +2 more sources
Computed tomographic myelography of the cranial cervical spine in Warmblood horses with no spinal pathology-Inter- and intravertebral ratios and distribution of contrast columns in neutral and flexed cervical spine. [PDF]
Abstract Background Computed tomographic myelography (CTM) and radiographic myelography (RxM) are diagnostic for extradural spinal cord compression, but knowledge about the contrast distribution in flexion and normal position of nonaffected horses is lacking.
Hellige M +6 more
europepmc +2 more sources
Condylar fracture location is correlated to exercise history in Thoroughbred racehorses. [PDF]
Abstract Background Condylar fractures are a major cause of morbidity and mortality in Thoroughbred racehorses. Condylar fractures have a variety of fracture configurations that suggest there may be differences in aetiopathogenesis. Objective To determine if exercise history differs with condylar fracture location in a population of Thoroughbred ...
Bergstrom TC +4 more
europepmc +2 more sources
Abstract Background The inter‐relationship between equine thoracolumbar motion and muscle activation during normal locomotion and lameness is poorly understood. Objective To compare thoracolumbar and pelvic kinematics and longissimus dorsi (longissimus) activity of trotting horses between baseline and induced forelimb (iFL) and hindlimb (iHL) lameness.
Tijn J. P. Spoormakers +8 more
wiley +1 more source
Abstract Background Both type 1 (PSSM1) and type 2 polysaccharide storage myopathy (PSSM2) are characterised by aggregates of abnormal polysaccharide in skeletal muscle. Whereas the genetic basis for PSSM1 is known (R309H GYS1), the cause of PSSM2 in Quarter Horses (PSSM2‐QH) is unknown and glycogen concentrations not defined.
Stephanie J. Valberg +7 more
wiley +1 more source
Background – Mycophenolate mofetil (MMF) is the prodrug of mycophenolic acid (MPA) which acts as an immunosuppressive agent. During the biotransformation of MMF to MPA, additional metabolites including MPA phenol glucuronide (MPAG), MPA acyl glucuronide (AcMPAG) and MPA phenol glucoside (MPG) are formed.
Dylan L. Burroughs +6 more
wiley +1 more source
Foram utilizados 159 cavalos Pampa, registrados na Associação Brasileira dos Criadores de Cavalo Pampa, e um grupo-controle, de 32 cavalos da raça Paint, ambos os grupos provenientes de plantéis de diferentes regiões brasileiras, com o objetivo de ...
E.G.A. Coelho +2 more
doaj +1 more source

