Results 211 to 220 of about 103,123 (277)

Global ethnic disparities in cerebral small vessel disease imaging markers and vascular risk factors: a systematic review and meta‐analysis

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract Ethnic disparities in cerebral small vessel disease (CSVD) have been reported, but no systematic synthesis has compared markers and vascular risk factors across populations. We conducted a PROSPERO‐registered systematic review and meta‐analysis (CRD42024518105) including over two million community‐dwelling adults.
Nikita K. Husein   +6 more
wiley   +1 more source

Plasma and neuroimaging biomarkers of small vessel disease and Alzheimer's disease in a diverse cohort: MESA

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Little is known about how Alzheimer's disease (AD) plasma biomarkers relate to cerebral small vessel disease (cSVD) neuroimaging biomarkers. METHODS The study involved 251 Wake Forest Multi‐Ethnic Study of Atherosclerosis (MESA) Exam 6 participants with plasma AD biomarkers, magnetic resonance imaging, amyloid positron emission ...
Samuel N. Lockhart   +22 more
wiley   +1 more source

Female‐biased astrocytic priming shapes early locus coeruleus vulnerability in an Aβ oligomer milieu

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION The locus coeruleus (LC) is an early site of Alzheimer's disease (AD) pathology, yet the role of brainstem astrocytes in early, sex‐dependent vulnerability remains unclear. METHODS In 2‐ to 3‐month‐old APP/PS1 mice, we combined in vivo proton magnetic resonance spectroscopy (MRS) of the brainstem with region‐resolved molecular ...
Srishti Kushwaha   +4 more
wiley   +1 more source

Rural-urban differences in lipid abnormalities among middle-aged and older Indians. [PDF]

open access: yesBMC Public Health
Chatterjee P   +5 more
europepmc   +1 more source

Falls predict faster progression to Alzheimer's dementia

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION In preclinical Alzheimer's disease (AD), amyloid accumulates in the brain while individuals remain cognitively unimpaired (Clinical Dementia Rating® [CDR] = 0). Differentiating trajectories of healthy aging and preclinical AD is challenging as both are associated with age‐related impairments (e.g., falls).
Audrey A. Keleman   +9 more
wiley   +1 more source

Virtual healthcare compared to hospital care for acute and post‐acute illness in adults: A systematic review and meta‐analysis of randomized controlled trials

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 374-395, February 2026.
Aim To evaluate the clinical effectiveness, cost‐effectiveness, quality of life (QoL) and patient/caregiver satisfaction associated with VWs/HaH vs. traditional inpatient care in adults with acute or post‐acute illness. Methods We conducted a systematic review and meta‐analysis of randomized controlled trials (RCTs), following PRISMA 2020 guidelines ...
Rana A. Malhis   +6 more
wiley   +1 more source

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