Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles [PDF]
CBR hydroxamidines are small-molecule inhibitors of bacterial RNA polymerase (RNAP) discovered through high-throughput screening of synthetic-compound libraries. CBR pyrazoles are structurally related RNAP inhibitors discovered through scaffold hopping from CBR hydroxamidines. CBR hydroxamidines and pyrazoles selectively inhibit Gram-negative bacterial
Feng, Yu +11 more
openaire +2 more sources
Survival and persistence of Nipah virus in blood and tissue culture media
Nipah virus (NiV) infection is a newly emerging zoonosis that causes severe disease in humans. Nipah virus is one of the lesser studied of the WHO emerging pathogens for which research is a priority.
Sophie J. Smither +5 more
doaj +1 more source
Reduction of pavement thickness using a subgrade layer treated by different techniques
A range of stabilisers for poor quality subgrade soils have been developed to promote road constructions. Many of them are becoming more popular depending on their effectiveness.
Raquim N. Zehawi +2 more
doaj +1 more source
Historically, disease progression in animal models of Q fever has been carried out using PCR to monitor the presence of Coxiella burnetii DNA in the host.
M. Gill Hartley +6 more
doaj +1 more source
Stabilization of Subgrade Soil for Highway by Recycled Polyester Fiber [PDF]
Subgrade soil stabilization is one of the primary and major processes in the construction of any highway; also environmental authorities are concerned about the growing amount of polyethylene (PET) bottles produced by household sectors.
Foad Changizi, Abdolhosein Haddad
doaj +1 more source
A Case Based Reasoning Coupling Multi-Criteria Decision Making with Learning and Optimization Intelligences: Application to Energy Consumption [PDF]
Optimization energy is a technique helpful to manage electricity consumption of home devices according tothe electric system. CBR is used to predict consumption but lacks to be generic.
Naomi Tchomté +5 more
doaj +1 more source
CMB and Large Scale Structure as a test of Mixed Models with n>1 [PDF]
We compute CBR anisotropies in mixed models with different hot components, including neutrinos or volatile HDM arising from the decay of heavier particles.
Bahcall +54 more
core +3 more sources
A literature review of expert problem solving using analogy [PDF]
We consider software project cost estimation from a problem solving perspective. Taking a cognitive psychological approach, we argue that the algorithmic basis for CBR tools is not representative of human problem solving and this mismatch could account ...
Mair, C, Martincova, M, Shepperd, MJ
core +1 more source
The Effect of Gravitational Scattering on the Anisotropy of the Cosmic Background Radiation [PDF]
The homogeneity of the cosmic microwave background radiation (CBR) is one of the most severe constraint for theories of the structure formation in the universe. We investigated the effect of the gravitational scattering (lensing) of galaxies, clusters of
Ebisuzaki, Toshikazu +2 more
core +2 more sources
Quantum to Classical Transition from the Cosmic Background Radiation [PDF]
We have revisited the Ghirardi-Rimini-Weber-Pearle (GRWP) approach for continuous dynamical evolution of the state vector for a macroscopic object. Our main concern is to recover the decoupling of the state vector dynamics for the center-of-mass (CM) and
A. Isar +31 more
core +2 more sources

