Results 31 to 40 of about 315,394 (267)

Constrained basin stability for studying transient phenomena in dynamical systems

, 2016
Transient dynamics are of large interest in many areas of science. Here, a generalization of basin stability (BS) is presented: constrained basin stability (CBS) that is sensitive to various different types of transients arising from finite size ...
Donges, Jonathan, Jegminat, Jannes, Kurths, Jürgen, van Kan, Adrian   +3 more
core   +1 more source

GÖLLER YÖRESİNDE SÜRDÜRÜLEBİLİRLİK VE DİRENÇLİLİK

Journal of Management Theory and Practices Research, 2021
Göller; insan toplumlarında içme suyu temini, su ürünleri yetiştiriciliği, tarım arazilerinin sulanması, rekreasyon, enerji üretimi, atık su arıtımı, sel ve kuraklık kontrolü olmak üzere çok çeşitli ekosistem hizmetleri sunar.
Hilal Tulan Işıldar, Özge Yalçıner Ercoşkun   +1 more
doaj  

Erfaringer fra et rollespil

Dansk Universitetspaedagogisk Tidsskrift, 2020
Denne artikel tager udgangspunkt i et rollespil, som bruges i eksamenskurser for adjunkter og eksterne undervisere, hvor spillet er det metodiske centrum.
Jens Kjær Riemer, Jens Tofteskov, Erik Caparros Højbjerg   +2 more
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Analysis of Spatially-Coupled Counter Braids [PDF]

, 2015
A counter braid (CB) is a novel counter architecture introduced by Lu et al. in 2007 for per-flow measurements on high-speed links. CBs achieve an asymptotic compression rate (under optimal decoding) that matches the entropy lower bound of the flow size ...
Amat, Alexandre Graell i, Rosnes, Eirik
core   +2 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

On the optical and X-ray afterglows of gamma ray bursts

, 2001
We severely criticize the consuetudinary analysis of the afterglows of gamma-ray bursts (GRBs) in the conical-ejection fireball scenarios. We argue that, instead, recent observations imply that the long-duration GRBs and their afterglows are produced by ...
A. Dar, A. De Rújula, Akerlof, Andersen, Bendarz, Berger, Beuermann, Bhargavi, Bjornsson, Bloom, Bloom, Bloom, Bloom, Bloom, Brainerd, Burenin, Castander, Castander, Castro-Tirado, Castro-Tirado, Castro-Tirado, Castro-Tirado, Castro-Tirado, Cline, Costa, Cranc, Dal Fiume, Dar, Dar, Dar, Dar, Dar, De Rújula, Diercks, Djorgovski, Djorgovski, Djorgovski, Frontera, Fruchter, Fruchter, Fruchter, Fynbo, Fynbo, Gabuzda, Galama, Galama, Galama, Garcia, Garnavich, Garnavich, Garnavich, Ghisellini, Goodman, Goodman, Guarnieri, Halpern, Halpern, Halpern, Halpern, Halpern, Harrison, Heger, Higdon, Higdon, Hjorth, Hjorth, Hjorth, Holland, Holland, Holland, Huang, Huang, Israel, Iwamoto, Jensen, Jha, Kedziora-Chudczer, Kennicut, Klose, Kotani, Kulkarni, Kulkarni, Kulkarni, Kumar, Levine, Loeb, MacFadyen, MacFadyen, Margon, Masetti, Meegan, Meszaros, Meszaros, Meszaros, Metzger, Mirabel, Mirabel, Moderski, Odewahn, Owens, Paczynski, Paczynski, Pedersen, Pedichini, Pian, Pian, Piran, Piran, Piro, Price, Rees, Reichart, Reichart, Rhoads, Rhoads, Rhoads, Rodriguez, S. Dado, Sagar, Sagar, Sagar, Sahu, Sahu, Sahu, Sari, Schlegel, Shaviv, Sokolov, Sokolov, Spruit, Stanek, Tingay, van den Bergh, van Dyk, van Paradijs, Veillet, Veillet, Vreeswijk, Vreeswijk, Vreeswijk, Wieringa, Wijers, Woosley, Woosley, Zharikov   +144 more
core   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source