Results 21 to 30 of about 62,162 (126)

Increasing the bulk of the 1TEL–target linker and retaining the 10×His tag in a 1TEL–CMG2‐vWa construct improves crystal order and diffraction limits

Acta Crystallographica Section D, Volume 79, Issue 10, Page 925-943, October 2023., 2023
Using a 1TEL–CMG2‐vWa construct, evidence is provided to support limiting the flexibility of linkers between TELSAM and proteins of interest and considering retaining polyhistidine purification tags in TELSAM‐fusion constructs. The phenomenon of TELSAM‐polymer flipping is also identified and a correction strategy is developed.TELSAM‐fusion ...
Parag L. Gajjar, Maria J. Pedroza Romo, Celeste M. Litchfield, Miles Callahan, Nathan Redd, Supeshala Nawarathnage, Sara Soleimani, Jacob Averett, Elijah Wilson, Andrew Lewis, Cameron Stewart, Yi-Jie Tseng, Tzanko Doukov, Andrey Lebedev, James D. Moody   +14 more
wiley   +1 more source

Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications

MedComm, Volume 4, Issue 3, June 2023., 2023
The reversible and irreversible protein posttranslational modifications, such as acetylation, methylation, phosphorylation, ubiquitination, glycosylation, SUMOylation, and redox modifications, are essential regulators in organisms and cells. This work systematically summarizes the features, regulatory mechanisms, substrates, functions, and related ...
Qian Zhong, Xina Xiao, Yijie Qiu, Zhiqiang Xu, Chunyu Chen, Baochen Chong, Xinjun Zhao, Shan Hai, Shuangqing Li, Zhenmei An, Lunzhi Dai   +10 more
wiley   +1 more source

A temperature‐compensated linear GaAs HBT power amplifier for small‐cell applications in −25 to 125∘C$^\circ \rm C$ lunar environment

Electronics Letters, Volume 58, Issue 18, Page 684-686, August 2022., 2022
Abstract A two‐stage 920–960 MHz power amplifier (PA) in GaAs heterojunction bipolar transistor (HBT) process is demonstrated for small‐cell communications in the lunar environment. To cope with the temperature fluctuations during lunar days, a novel complementary to absolute temperature (CTAT) biasing scheme is proposed for the PA to achieve an ultra ...
Jiajin Li, Gary Zhang, Chang Yang
wiley   +1 more source

Intracranial mesenchymal tumors with FET‐CREB fusion are composed of at least two epigenetic subgroups distinct from meningioma and extracranial sarcomas

Brain Pathology, Volume 32, Issue 4, July 2022., 2022
We studied the epigenomic landscape of intracranial mesenchymal tumor with FET‐CREB fusion, an emerging CNS tumor entity that occurs primarily in children and young adults. These tumors resolved into two epigenetic subgroups with divergent clinical outcomes that were distinct from meningiomas and all analyzed extracranial sarcomas.
Emily A. Sloan, Rohit Gupta, Christian Koelsche, Jason Chiang, Javier E. Villanueva‐Meyer, Sanda Alexandrescu, Jennifer M. Eschbacher, Wesley Wang, Manuela Mafra, Nasir Ud Din, Emily Carr‐Boyd, Michael Watson, Michael Punsoni, Angelica Oviedo, Ahmed Gilani, Bette K. Kleinschmidt‐DeMasters, Dylan J. Coss, M. Beatriz Lopes, Alyssa Reddy, Sabine Mueller, Soo‐Jin Cho, Andrew E. Horvai, Julieann C. Lee, Melike Pekmezci, Tarik Tihan, Andrew W. Bollen, Fausto J. Rodriguez, David W. Ellison, Arie Perry, Andreas von Deimling, Susan M. Chang, Mitchel S. Berger, David A. Solomon   +32 more
wiley   +1 more source

Peer review of the pesticide risk assessment of the active substance bixlozone. [PDF]

EFSA J
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State, The Netherlands for the pesticide active substance bixlozone are reported. The context of the peer review was that required by Regulation (EC) No 1107/2009
European Food Safety Authority (EFSA), Álvarez F, Arena M, Auteri D, Leite SB, Binaglia M, Castoldi AF, Chiusolo A, Colagiorgi A, Colas M, Crivellente F, De Lentdecker C, De Magistris I, Egsmose M, Fait G, Ferilli F, Santonja GG, Gouliarmou V, Halling K, Nogareda LH, Ippolito A, Istace F, Jarrah S, Kardassi D, Kienzler A, Lanzoni A, Lava R, Leuschner R, Linguadoca A, Louisse J, Lythgo C, Magrans O, Mangas I, Mioč A, Miron I, Molnar T, Padovani L, Padricello V, Panzarea M, Parra Morte JM, Rizzuto S, Romac A, Rortais A, Santos M, Serafimova R, Sharp R, Szentes C, Terron A, Theobald A, Tiramani M, Vianello G, Villamar-Bouza L.   +51 more
europepmc   +2 more sources

Appropriate Levels of Detail in 3-D Visualisation: the House of the Surgeon, Pompeii

Internet Archaeology, 2008
The use of three-dimensional computer models in archaeological projects is a relatively new but rapidly growing area, both as a means of presenting research to the public and also as an aid to interpretation.
P.S. Murgatroyd
doaj   +1 more source

DB-HERITAGE Building Materials Data Aggregation in ARIADNE - challenges and opportunities

Internet Archaeology, 2023
DB-HERITAGE provides open and free sharing of wide-ranging technical data on hundreds of samples of building materials from diverse periods, extracted from Portuguese built heritage all over the world.
Maria J. Correia, António Santos Silva
doaj   +1 more source

Review of The Museum of the World [website]

Internet Archaeology, 2017
The British Museum, in partnership with the Google Cultural Institute, has developed a digital interface featuring selected objects from their collections: The Museum of the World. The mission of the project is to make knowledge and culture of the 'whole
Samantha Lash
doaj   +1 more source

Aggregating Coin Find Data to the ARIADNE Portal. Challenges of using the Getty AAT for a specialist domain

Internet Archaeology, 2023
Integration of data on coin finds into the ARIADNE portal presents a number of challenges, partly related to the use of the Getty AAT as a controlled vocabulary, in particular its incomplete coverage and hierarchical structure.
David Wigg-Wolf, Anna-Lisa Pfeiffer, Karsten Tolle   +2 more
doaj   +1 more source

The palaeochannel record in the Trent Valley UK: contributions towards cultural heritage management

Internet Archaeology, 2007
The Trent Valley is one of Britain's major river systems, and the dynamic history of the river has produced a rich and varied palaeochannel record. This paper reports on a catchment-scale survey of surface-visible palaeochannels within the Holocene ...
Steve Baker
doaj   +1 more source