Results 161 to 170 of about 208,608 (296)

The Endothelial CXCR Family in Vascular Health and Disease

open access: yesiNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu   +4 more
wiley   +1 more source

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

open access: yesiNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang   +3 more
wiley   +1 more source

Multiobjective Simulation–Optimization of Crop Allocation and Water Resources in Canal Command Areas Using Genetic Algorithms

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT This study develops an integrated simulation–optimization framework for sustainable crop allocation and water resource management in the Bargarh Canal Command (BCC), eastern India. Efficient irrigation allocation remains a critical challenge due to competing demands, groundwater–surface water interactions and environmental constraints ...
Priyanka Mohapatra   +2 more
wiley   +1 more source

HMGA1 is associated with unfavorable outcome and accelerates the aggressiveness of cholangiocarcinoma. [PDF]

open access: yesSAGE Open Med
Phumphu R   +12 more
europepmc   +1 more source

Somatosensory Disturbance and Long‐Term Exposure to Methylmercury: A Comprehensive Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Chronic exposure to methylmercury remains a significant public health concern, particularly in populations with high fish consumption. Somatosensory disturbances are among the most frequently reported neurological manifestations, even at exposure levels below internationally established safety thresholds. This review aims to synthesize current
Leonardo Breno do Nascimento de Aviz   +9 more
wiley   +1 more source

The Clinicopathological Characteristics and Prognosis of Cholangiolocarcinoma: A Multicenter Study With a Central Pathology Review

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Cholangiolocarcinoma (CLC) is a rare liver cancer with ≥ 80% ductular configuration (DC). Given its rarity, its clinicopathological characteristics remain poorly understood, and its status as a distinct disease entity remains controversial.
Takamichi Ishii   +22 more
wiley   +1 more source

Machine learning for population-level risk prediction of future cholangiocarcinoma. [PDF]

open access: yesEBioMedicine
van Haag F   +21 more
europepmc   +1 more source

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