Results 1 to 10 of about 12,380 (194)

A Survey on Current-Mode Interfaces for Bio Signals and Sensors [PDF]

open access: yesSensors, 2023
In this study, a review of second-generation voltage conveyor (VCII) and current conveyor (CCII) circuits for the conditioning of bio signals and sensors is presented.
Massimo Scarsella   +4 more
doaj   +2 more sources

Age-related immune states and PD-1 blockade: mechanisms and strategies for the elderly [PDF]

open access: yesJournal for ImmunoTherapy of Cancer
Aging impairs antitumor immunity and may reduce the efficacy of immune checkpoint inhibitors (ICIs). However, the underlying mechanisms remain unclear. Building on our recent findings, we review three key mechanisms of CD8+ T-cell aging: elevated T-cell ...
Tomonori Yaguchi   +2 more
doaj   +2 more sources

Single-nucleus RNA sequencing and deep tissue proteomics reveal distinct tumour microenvironment in stage-I and II cervical cancer [PDF]

open access: yesJournal of Experimental & Clinical Cancer Research, 2023
Background Cervical cancer (CC) is the 3rd most common cancer in women and the 4th leading cause of deaths in gynaecological malignancies, yet the exact progression of CC is inconclusive, mainly due to the high complexity of the changing tumour ...
Xiaosong Liu   +9 more
doaj   +2 more sources

Analog Front-End ASIC for Compact Silicon Photomultiplier Sensor Interfaces in Mixed-Signal Systems [PDF]

open access: yesSensors
We present a mixed-signal front-end ASIC designed for compact Silicon Photomultiplier (SiPM) sensor interfaces, implemented in the AMS 0.35 µm CMOS technology.
Davide Badoni   +7 more
doaj   +2 more sources

Inverter-Based Low-Voltage CCII- Design and Its Filter Application [PDF]

open access: yesRadioengineering, 2013
This paper presents a negative type second-generation current conveyor (CCII-). It is based on an inverter-based low-voltage error amplifier, and a negative current mirror. The CCII- could be operated in a very low supply voltage such as ±0.5V.
Y. S. Hwang   +3 more
doaj   +2 more sources

Drug design for cyclin-dependent kinase 9 (CDK9) inhibitors in silico [PDF]

open access: yesBiochemistry and Biophysics Reports
Despite the potential of cyclin-dependent kinase 9 (CDK9) as a novel target for various malignancies and HIV replication in infected cells, no effective inhibitors have been developed.
Kaori Asamitsu   +2 more
doaj   +2 more sources

Phenotypic and genotypic characterisation of Burkholderia cenocepacia J2315 mutants affected in homoserine lactone and diffusible signal factor-based quorum sensing systems suggests interplay between both types of systems. [PDF]

open access: yesPLoS ONE, 2013
Many putative virulence factors of Burkholderia cenocepacia are controlled by various quorum sensing (QS) circuits. These QS systems either use N-acyl homoserine lactones (AHL) or cis-2-dodecenoic acid ("Burkholderia diffusible signal factor", BDSF) as ...
Claudia Udine   +7 more
doaj   +5 more sources

A 0.18µm CMOS DDCCII for Portable LV-LP Filters [PDF]

open access: yesRadioengineering, 2013
In this paper a current mode very low voltage (LV) (1V) and low power (LP) (21 µW) differential difference second generation current conveyor (CCII) is presented.
V. Stornelli, G. Ferri
doaj   +2 more sources

Novel CCII-based Field Programmable Analog Array and its Application to a Sixth-Order Butterworth LPF [PDF]

open access: yesRadioengineering, 2013
In this paper, a field programmable analog array (FPAA) is proposed. The proposed FPAA consists of seven configurable analog blocks (CABs) arranged in a hexagonal lattice such that the CABs are directly connected to each other.
S. A. Mahmoud, E. A.Soliman
doaj   +2 more sources

Current-Mode CCII+ Based Oscillator Circuits using a Conventional and a Modified Wien-Bridge with All Capacitors Grounded [PDF]

open access: yesRadioengineering, 2011
The paper deals with a pair of current-mode sine-wave oscillator circuits. Both these circuits are implemented using positive second-generation current conveyors (CCII+).
J. Bajer, A. Lahiri, D. Biolek
doaj   +2 more sources

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