Results 21 to 30 of about 28,475 (220)

Beyond Medical Therapy—An Update on Heart Failure Devices

Journal of Cardiovascular Development and Disease
Heart failure (HF) is a complex and progressive disease marked by substantial morbidity and mortality rates, frequent episodes of decompensation, and a reduced quality of life (QoL), with severe financial burden on healthcare systems.
Luigi Falco, Fabio Valente, Aldo De Falco, Raffaele Barbato, Luigi Marotta, Davide Soviero, Luigi Mauro Cantiello, Carla Contaldi, Benedetta Brescia, Enrico Coscioni, Giuseppe Pacileo, Daniele Masarone   +11 more
doaj   +1 more source

Co–Cr–Mo alloy binding peptide as molecular glue for constructing biomedical surfaces

Journal of Applied Biomaterials & Functional Materials, 2020
The mechanical properties of Co–Cr–Mo (CCM) alloys are advantageous in various biomedical applications. However, because of their bioinert surface, CCM alloys exhibit poor endothelial cell attachment properties; thus, problems of biocompatibility remain.
Satoshi Migita, Kosuke Sakashita, Yuta Saito, Suyalatu, Tomohiko Yamazaki   +4 more
doaj   +1 more source

Synthesis of TPGS/Curcumin Nanoparticles by Thin-Film Hydration and Evaluation of Their Anti-Colon Cancer Efficacy In Vitro and In Vivo

Frontiers in Pharmacology, 2019
Curcumin (CCM) has many potential uses in anticancer chemotherapy, but its low water solubility poses a major problem, preventing its translation into clinical use.
Hong Li, Hong Li, Liping Yan, Edith K.Y. Tang, Zhen Zhang, Wei Chen, Guohao Liu, Guohao Liu, Jingxin Mo   +8 more
doaj   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Searching for coherence in a correspondence world [PDF]

Judgment and Decision Making, 2009
In this paper, I trace the evolution of the aircraft cockpit as an example of the transformation of a probabilistic environment into an ecological hybrid, that is, an environment characterized by both probabilistic and deterministic features and elements.
Kathleen L. Mosier
doaj  

Quality contract ‘prevention of postoperative delirium in the care of elderly patients’ study protocol: a non-randomised, pre–post, monocentric, prospective trial

BMJ Open, 2023
Introduction Postoperative delirium (POD) is seen in approximately 15% of elderly patients and is related to poorer outcomes. In 2017, the Federal Joint Committee (Gemeinsamer Bundesausschuss) introduced a ‘quality contract’ (QC) as a new instrument to ...
Sascha Treskatsch, Claudia Spies, Sophie K Piper, Jochen Kruppa, Felix Balzer, Ursula Marschall, Kathrin Scholtz, Dieter Schmidt, Joern Kiselev, Moritz Höft, Fatima Yürek, Julian-Dominic Zimmermann, Elisa Weidner, Armin Hauß, Enrico Dähnert, Daniel Hadzidiakos, Natia Sichinava, Oscar Andrés Retana Romero, Laerson Hoff, Rudolf Mörgeli, Lennart Junge, Luzie Grüner, Antonia Eva Maria Harborth, Lisa Eymold, Tuba Gülmez, Elke Falk, Franziska Landgraf, Andreas Hölscher, Mani Rafii   +28 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Child contact management in high tuberculosis burden countries: A mixed-methods systematic review.

PLoS ONE, 2017
Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide. Considering the World Health Organization recommendation to implement child contact management (CCM) for TB, we conducted a mixed-methods systematic review to summarize CCM ...
Daria Szkwarko, Yael Hirsch-Moverman, Lienki Du Plessis, Karen Du Preez, Catherine Carr, Anna M Mandalakas   +5 more
doaj   +1 more source

Enabling Digital Continuity in Virtual Manufacturing for Eco‐Efficiency Assessment of Lightweight Structures by Means of a Domain‐Specific Structural Mechanics Language: Requirements, Idea and Proof of Concept

Advanced Engineering Materials, EarlyView.
This article presents a solver‐agnostic domain‐specific language (DSL) for computational structural mechanics that strengthens interoperability in virtual product development. Using a hierarchical data model, the DSL enables seamless exchange between diverse simulation tools and numerical methods.
Martin Rädel, Andreas Schuster, Felix Schoenitz, Jean Lefèvre   +3 more
wiley   +1 more source

Wine as a Potential Source of Probiotic Bacteria

Scientific Papers Animal Science and Biotechnologies, 2023
Wine has long been under the view of researchers to test it for prospective benefits to human health. Many recent studies have claimed how moderate consumption of wine, can be beneficial for us.
Miroslava Kačániová, Attila Kántor, Soňa Felsöciová, Jana Žiarovská, Simona Kunová, Margarita Terentjeva, Eva Ivanišová   +6 more
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