Co-Circulation of Canine Coronavirus I and IIa/b with High Prevalence and Genetic Diversity in Heilongjiang Province, Northeast China. [PDF]
PLoS ONE, 2016 To trace the evolution of canine coronavirus (CCoV), 201 stool samples from diarrheic dogs in northeast China were subjected to reverse transcription-polymerase chain reactions (RT-PCRs) targeting the partial M and S genes of CCoV, followed by an ...
Xinyu Wang +13 more
doaj +1 more source
A One Health Perspective on Canine Coronavirus: A Wolf in Sheep’s Clothing?
Microorganisms, 2023 Canine coronavirus (CCoV) is a positive-strand RNA virus generally responsible for mild-to-severe gastroenteritis in dogs. In recent years, new CCoVs with acquired pathogenic characteristics have emerged, turning the spotlight on the evolutionary ...
Alessio Buonavoglia +4 more
doaj +1 more source
Identification and phylogenetic analysis of two canine coronavirus strains
Animal Diseases, 2021 Canine coronavirus (CCoV), a member of the genus Alphacoronavirus, is an enveloped, single-stranded positive-sense RNA virus that responsible for gastroenteritis in dogs. In this study, two CCoV isolates were successfully propagated from 53 CCoV-positive
Junji Gan +4 more
doaj +1 more source
Antibiotics, 2023 Recent studies have demonstrated that 3-O-methylfunicone (OMF), a fungal secondary metabolite from Talaromyces pinophilus belonging to the class of funicone-like compounds, has antiviral activity against canine coronaviruses (CCoV), which causes ...
Claudia Cerracchio +8 more
doaj +1 more source
Frontiers in Microbiology, 2022 Canine coronavirus (CCoV) and feline coronavirus (FCoV) are endemic in companion animals. Due to their high mutation rates and tendencies of genome recombination, they pose potential threats to public health.
Hu Yang +23 more
doaj +1 more source
Circulation and Genetic Characterizations of Coronaviruses From Companion Animals in Chengdu, Southwest China: One-Year Postpandemic. [PDF]
Transbound Emerg DisCoronaviruses (CoVs) can cross species barriers and endanger public health. Despite reports on their circulation and evolution in companion animals during the pandemic, postpandemic surveillance remains crucial. Therefore, during the first postpandemic year, 309 samples from 263 companion animals (cats and dogs) in Chengdu, China, were detected for ...
Liao L +9 more
europepmc +2 more sources
Repeated instillations of bleomycin in male mice induce a perivascular remodeling at distance of fibrotic areas in the context of progressive pulmonary fibrosis. [PDF]
Animal Model Exp MedWe established a model of progressive pulmonary fibrosis via repeated intratracheal instillation (ITI) of leomycin (BLM) (A). Perivascular remodeling was observed in areas distant from the fibrotic areas and lesions induced by repeated ITI of BLM simulate those observed in IPF patients (B). Thus, this model has the capacity to track and investigate the
Yegen CH +9 more
europepmc +2 more sources
Molecular characterization of the FCoV-like canine coronavirus HLJ-071 in China
BMC Veterinary Research, 2021 Background According to the differences of antigen and genetic composition, canine coronavirus (CCoV) consists of two genotypes, CCoV-I and CCoV-II. Since 2004, CCoVs with point mutations or deletions of NSPs are contributing to the changes in tropism ...
Zhige Tian +6 more
doaj +1 more source
Recombinant Canine Coronaviruses in Dogs, Europe
Emerging Infectious Diseases, 2010 Coronaviruses of potential recombinant origin with porcine transmissible gastroenteritis virus (TGEV), referred to as a new subtype (IIb) of canine coronavirus (CCoV), were recently identified in dogs in Europe.
Nicola Decaro +7 more
doaj +1 more source
Canine Coronavirus Activates Aryl Hydrocarbon Receptor during In Vitro Infection
Viruses, 2022 The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that interacts with substrates, including microbial metabolites.
Claudia Cerracchio +3 more
doaj +1 more source