Results 121 to 130 of about 180,784 (340)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Understanding key elements in establishing a social license for CCS: An empirical approach
This paper presents results of empirical research with the broad aim of exploring societal responses to CO2 storage, framed around the concept of social license to operate (SLO).
C. Gough, R. Cunningham, S. Mander
semanticscholar +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Studies on �Kinnow� (Citrus reticulata Blanco.) Decline in Relation to Soil-Plant Nutritional Status
Kinnow decline was studied in relation to soil plant nutritional status under semi arid condition of Hisar (India). There were no differences between the soil pH, electrical conductivity and calcium carbonate of healthy and declining trees.
Parveen KUMAR +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The distribution of copper (Cu) among various chemical forms and its availability to oat nutrition may vary significantly in response to changing soil properties.
NARENDER NARENDER +4 more
doaj +1 more source
The Quest CCS Project: 1st Year Review Post Start of Injection
In September 2012, the final investment decision was taken to move ahead with the Quest Carbon Capture and Storage (CCS) project in Alberta, Canada. Quest is the world's first CCS project linked to an oil sands bitumen upgrader. The operator is Shell and
L. Rock +14 more
semanticscholar +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Tekinay, Şirin (2016). "Türkiye’de CC; Türkiye ve CC" Creative Commons Türkiye Lansmanı, 11 Mart 2016. Özyeğin Üniversitesi, İstanbul.
openaire +1 more source

