Cholesterol crystal formation and embolism in the central nervous system and their potential role in Alzheimer's disease. [PDF]
Houmani A +9 more
europepmc +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Challenges in Collaborative Long-Term Health Management for Childhood Cancer Survivors Between General Physicians and Pediatric Oncologists in Japan: A Qualitative Study. [PDF]
Kanke S +7 more
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Plasma Steroids as Biomarkers of Congestion and Predictors of Prognosis in Acute Heart Failure During the Vulnerable Phase. [PDF]
Fan Y +5 more
europepmc +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Inheritance Patterns of Flower Color Traits in Self-Pollinated and Cross-Pollinated Progeny of Four Commercial <i>Catharanthus roseus</i> Cultivars. [PDF]
Huang TH, Lu YC, Shen RS.
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
TIMSImaging: an open and interoperable workflow for trapped ion mobility mass spectrometry imaging data processing and visualization. [PDF]
Zhu Y +7 more
europepmc +1 more source
Korean Society of Interventional Cardiology Expert Consensus for the Management of Chronic Coronary Syndrome: Part 1. [PDF]
Lee JM +20 more
europepmc +1 more source

