Results 11 to 20 of about 15,701 (134)

CD1 molecules: Beyond antigen presentation

Molecular Immunology
CD1 molecules are well known for their role in binding and presenting lipid antigens to mediate the activation of CD1-restricted T cells. However, much less appreciated is the fact that CD1 molecules can have additional "unconventional" roles which ...
Patricia Barral
exaly   +2 more sources

CD1 and mycobacterial lipids activate human T cells

Immunological Reviews, 2015
For decades, proteins were thought to be the sole or at least the dominant source of antigens for T cells. Studies in the 1990s demonstrated that CD1 proteins and mycobacterial lipids form specific targets of human αβ T cells.
Ildiko Van Rhijn, David Branch Moody
exaly   +1 more source

Comparison of Electrophysical Characteristics of Undoped Cd1 – xZnxTe, Cd1 – yMnyTe and Cd1 – x – yZnxMnyTe (x, y ≤ 0,1) Crystals [PDF]

, 2016
Проведено аналіз температурної залежності (Т = 80÷360 К) електрофізичних властивостей кристалів Cd1 – xZnxTe, Cd1 – yMnyTe та Cd1 – x – yZnxMnyTe (x, y ≤ 0,1), вирощених вертикальним методом Бріджмена. Встановлено, що в кристалах Cd1 – xZnxTe провідність
Дремлюженко, С., Копач, О., Опанасюк, Анатолій Сергійович, Никонюк, Є., Opanasiuk, Anatolii Serhiiovych, Фочук, П., Солодін, C., Опанасюк, Анатолий Сергеевич, Захарук, З.   +8 more
core   +2 more sources

Molecular characterisation of Ovine CD1 [PDF]

, 1994
The CD1 molecules are a family of ß2microglobulin- associated glycoproteins with strong structural homology, but weaker sequence homology, to the MHC class I antigens. In contrast to the classical class I antigens, CD1 molecules exhibit restricted
Ferguson, Elaine Dorothea
core   +3 more sources

CD1 expression and CD1-restricted T cell activity in normal and tumour-bearing human liver [PDF]

, 2007
CD1d-restricted natural killer T (NKT) cells expressing invariant Vα14Jα18 T cell receptor α-chains are abundant in murine liver and are implicated in the control of malignancy, infection and autoimmunity.
Hogan, Andrew E., Exley, Mark A., Margaret O’Brien, Steven A. Porcelli, Andrew E. Hogan, Tony Kenna, O’Brien, Margaret, Hogan, Andrew, Porcelli, Steven A., John E. Hegarty, Mark A. Exley, Cliona O’Farrelly, O’Farrelly, Cliona, Derek G. Doherty, O'Farrelly, Cliona, Hegarty, John E., Kenna, Tony, Doherty, Derek G., O'Brien, Margaret   +18 more
core   +1 more source

A novel self-lipid antigen targets human T cells against CD1c(+) leukemias [PDF]

, 2014
T cells that recognize self-lipids presented by CD1c are frequent in the peripheral blood of healthy individuals and kill transformed hematopoietic cells, but little is known about their antigen specificity and potential antileukemia effects.
Lepore, Marco, Locatelli, Franco, Giulia Casorati, Paul Jenö, Chengfeng Xia, Consonni, Michela, S. R. Gundimeda, P. Jeno, Daniela Montagna, C. Bonini, Alessandra Forcina, G. Casorati, Claudia de Lalla, Franco Locatelli, Sansano, Sebastiano, Bonini, Chiara, Piccolo, Francesco, Xia, Chengfeng, Z. Li, P. Dellabona, Garavaglia, Claudio, H. Gsellinger, F. Piccolo, de Lalla, Claudia, Paolo Dellabona, G. Ni, F. Ciceri, Gundimeda, S. Ramanjaneyulu, Heiko Gsellinger, Häussinger, Daniel, Daniel Häussinger, Scelfo, Andrea, L. Mori, C. Garavaglia, Gennaro De Libero, A. Bondanza, Michela Consonni, Sebastiano Sansano, A. Forcina, Ciceri, Fabio, Jenö, Paul, Fabio Ciceri, M. Lepore, Attilio Bondanza, Gsellinger, Heiko, De Libero, Gennaro, S. Sansano, Bondanza, Attilio, Casorati, Giulia, D. Haussinger, Marco Lepore, C. de Lalla, G. De Libero, M. Consonni, Guanghui Ni, Lucia Mori, Li, Zhiyuan, Zhiyuan Li, Montagna, Daniela, Forcina, Alessandra, Andrea Scelfo, Mori, Lucia, S. Ramanjaneyulu Gundimeda, Chiara Bonini, Claudio Garavaglia, A. Scelfo, Francesco Piccolo, Ni, Guanghui, C. Xia, Dellabona, Paolo   +69 more
core   +1 more source

ODPOWIEDZIALNOŚĆ INWESTORA WOBEC PODWYKONAWCÓW (ART. 6471 § 5 K.C.) [PDF]

, 2017
The Liability of an Investor to a Subcontractor (Art. 6471 § 5 k.c.)SummaryThe article answers a question w hether an investor in case of a contract for construction works will be liable to a subcontractor also when he paid the latter all dues (including
Jędrejek, Grzegorz
core   +3 more sources

CD1 antigen presentation by human dendritic cells as a target for herpes simplex virus immune evasion.

, 2006
In contrast to MHC molecules, which present peptides, the CD1 molecules have been discovered to present lipid Ags to T cells. CD1-restricted T lymphocytes have been recently associated with resistance to virus infection.
Martin J. Raftery, Stefan H. E. Kaufmann, Raftery, Martin J, Kaufmann, Stefan H. E., Winau, Florian, Raftery, Martin J., Günther Schönrich, Kaufmann, Stefan HE, Ulrich E. Schaible, Schönrich, Günther, Florian Winau, Schaible, Ulrich E, Schaible, Ulrich E.   +12 more
core   +1 more source

CD1 displays its own negative regulators

, 2023
After two decades of the study of lipid antigens that activate CD1-restricted T cells, new studies show how autoreactive αβ T-cell receptors (TCRs) can directly recognize the outer surface of CD1 proteins in ways that are lipid-agnostic.
Adam Shahine, D. Branch Moody, Shahine, Adam, Jamie Rossjohn, Rossjohn, Jamie, Ildiko Van Rhijn, Moody, D. Branch, Van Rhijn, Ildiko   +7 more
core   +1 more source

Differential expression of ovine CD1 [PDF]

, 2000
Differential expression of ovine CD1 was examined using a combination of reverse transcription-polymerase chain reaction (RT-PCR) with sequence-specific primers and Northern and in situ hybridization techniques.
S. M. Rhind, Rhind, S M ; id_orcid, J. Hopkins, E. S. Grant, Hopkins, J, Grant, E S   +5 more
core   +1 more source