Results 281 to 290 of about 42,056 (305)
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Cancer Letters
Radiotherapy alters the tumor microenvironment and reprograms cellular metabolism. Transition of tumor cell phenotypes contributes to post-radiotherapy tumor recurrence.
Ting Sun +5 more
semanticscholar +1 more source
Radiotherapy alters the tumor microenvironment and reprograms cellular metabolism. Transition of tumor cell phenotypes contributes to post-radiotherapy tumor recurrence.
Ting Sun +5 more
semanticscholar +1 more source
Nano letters (Print)
Harnessing the potential of tumor-associated macrophages (TAMs) to engulf tumor cells offers promising avenues for cancer therapy. Targeting phagocytosis checkpoints, particularly the CD47-signal regulatory protein α (SIRPα) axis, is crucial for ...
Siyao Wang +10 more
semanticscholar +1 more source
Harnessing the potential of tumor-associated macrophages (TAMs) to engulf tumor cells offers promising avenues for cancer therapy. Targeting phagocytosis checkpoints, particularly the CD47-signal regulatory protein α (SIRPα) axis, is crucial for ...
Siyao Wang +10 more
semanticscholar +1 more source
CD47 and death signaling in the immune system
Apoptosis, 2000Receptor-mediated death signaling plays a critical role both in proper control of immune responses and in killing of target cells by T cells. In addition to the recognized death receptors which all belong to the tumor necrosis factor receptor family, recent studies suggest that also other cell surface antigens may be involved in apoptotic signaling in ...
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Cancer Research
Developing effective treatments for patients with head and neck squamous cell carcinoma (HNSCC) is a significant challenge. Cetuximab, a first-line targeted therapy for HNSCC, exhibits limited efficacy.
Bolei Li +7 more
semanticscholar +1 more source
Developing effective treatments for patients with head and neck squamous cell carcinoma (HNSCC) is a significant challenge. Cetuximab, a first-line targeted therapy for HNSCC, exhibits limited efficacy.
Bolei Li +7 more
semanticscholar +1 more source
Role of CD47 in Erythroid Cells and in Autoimmunity
Leukemia & Lymphoma, 2004The cell surface glycoprotein CD47 (Integrin-associated protein/IAP) was originally identified as a regulator of integrin-dependent responses to extracellular matrix proteins. However, CD47 is ubiquitously expressed, also by cells that do not express integrins. Thus, during the last few years, it has been shown that CD47 has several important functions
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[Research Progress of CD47-Related Signaling Pathway and the Role of CD47 in Pathogenic Infection].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2022CD47, a transmembrane glycoprotein widely expressed on the cell surface, is one of the important checkpoints through which cells escape innate immune surveillance. The important role of CD47-related signaling pathway and changes in expression level in immune regulation, pathogen infection and anti-tumor immunity has gradually come to be recognized.
Jing, Chen +3 more
openaire +1 more source