Results 101 to 110 of about 459,921 (305)
ELISPOT assay to measure antigen-specific murine CD8(+) T cell responses.
, 2001 The enzyme-linked immunospot technique (ELISPOT) relies on the visualization of cytokine secretion by individual T cells following in vitro stimulation with antigen. This assay has been developed and standardized for the quantitative detection of antigen-
Luzia H Carvalho +5 more
core +1 more source
JCI Insight, 2023 Maternal decidual CD8+ T cells must integrate the antithetical demands of providing immunity to infection while maintaining immune tolerance for fetal and placental antigens.
Shweta Mahajan +9 more
doaj +1 more source
Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells. [PDF]
PLoS ONE, 2011 Human CD8(+) regulatory T cells, particularly the CD8(+)CD28(-) T suppressor cells, have emerged as an important modulator of alloimmunity. Understanding the conditions under which these cells are induced and/or expanded would greatly facilitate their ...
Yuming Yu +8 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari +10 more
wiley +1 more source
Exposure to Abnormal Self Antigens During Non-Malignant Inflammatory Events Provides Immunological Defense Against Tumors [PDF]
, 2013 Cancer immunosurveillance is the body’s sentinel mechanism of recognizing and eliminating malignancy. Specifically, the immune system can mount a response against cancer through the recognition of tumor associated antigens (TAA). While studying two TAAs,
Iheagwara, Uzoma
core
Assessing Cd8 T Cell Number and Dysfunction in the Presence of Antigen [PDF]
The Journal of Experimental Medicine, 2001 CD8 T cells proliferate and differentiate into cytokine-secreting cytolytic effectors on encounter with viral antigens. As virus is cleared the activated T cells undergo apoptosis, but some survive and enter the memory pool where they persist indefinitely, slowly dividing in a relatively quiescent state until reactivation on reexposure to the antigen 1.
openaire +3 more sources
Investigations of mycobacteria-specific memoryy/effector T cell responses in HIV infected children receiving antiretroviral therapy [PDF]
, 2011 Includes abstract.Includes bibliographical references (leaves 170-210).Human immunodeficiency virus (HIV) infected children are at greater risk of developing tuberculosis disease, and might benefit from vaccination with novel TB vaccines. However, little
Tena-Coki, Nontobeko Gwendoline
core +1 more source
Advanced Materials, EarlyView.Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song +14 more
wiley +1 more source
Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo [PDF]
, 2004 Strategies to enhance the immunogenicity of tumors are urgently needed. Although vaccination with irradiated dying lymphoma cells recruits a tumor-specific immune response, its efficiency as immunogen is poor.
Zimmermann, VS +58 more
core +1 more source
PLoS Pathogens, 2013 It has long been known that multiple sclerosis (MS) is associated with an increased Epstein-Barr virus (EBV) seroprevalence and high immune reactivity to EBV and that infectious mononucleosis increases MS risk.
Daniela F Angelini +14 more
doaj +1 more source