Results 141 to 150 of about 21,801 (266)

Skeletal muscle adaptation to muscle activity and hypoxia: Differential structural and metabolic remodelling

The Journal of Physiology, EarlyView.
Abstract figure legend There has been controversy about the structural (capillary) response of skeletal muscle to altered O2 status, involving decreased supply (hypoxia) or increased demand (activity). Here we demonstrate that seven days of activation of skeletal muscle by indirect electrical stimulation led to significant expansion of the capillary ...
David Hauton, Roger W.P. Kissane, James McCullagh, Stuart Egginton   +3 more
wiley   +1 more source

Circulating microRNA signatures reveal core and reversible dysregulation in obesity via machine learning

The Journal of Physiology, EarlyView.
Abstract figure legend Machine learning analysis of circulating microRNA (miRNA) profiles identified a minimal set of biomarkers that distinguish individuals with obesity from lean individuals both before and after weight‐loss intervention. Comparative analyses revealed heterogeneous molecular responses to weight reduction, with some miRNAs showing ...
Yuan Yue, Rajesh Katare, Jeremiah Deng, Daniel Alencar Da Costa, Patrick Manning   +4 more
wiley   +1 more source

Mechanisms Underlying Cedazuridine-Mediated Enhancement of Oral Decitabine Bioavailability. [PDF]

Cancer Res Commun
Anabtawi N, Drabison T, Ham AF, Boeckman M, Stromatt JC, Orwick SJ, Buelow DR, Kaur T, Ahmed EA, Eisenmann ED, Govindarajan R, Sparreboom A, Baker SD.   +12 more
europepmc   +1 more source

Phenotyping Common Bean (Phaseolus vulgaris L.) Tolerance to Fomesafen and Imazamox Using Visible RGB Imaging Integrated With Multivariate Analysis

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT The common bean is vital for food security, but its productivity is often limited by competition with weeds, requiring the use of herbicides. The response of genotypes to herbicides such as fomesafen and imazamox is variable, and the traditional evaluation of phytotoxicity through visual methods is subjective.
Carlos Zacarias Joaquim Jr., Luan Tiago dos Santos Carbonari, Carina Lopes Djadjo, Charlene Barboza Bussolaro, Mauro Bitencourt de Souza, Vagner Muniz de Oliveira, Maria Fernanda Campos Rodrigues, Fernanda Cristina Schutz Gislon, Samara Campos do Nascimento, Aires da Costa, Jorge Luis Tejada, Paulo Henrique Cerutti, Altamir Frederico Guidolin, Jefferson Luís Meirelles Coimbra   +13 more
wiley   +1 more source

Use of Real-World Evidence in Health Technology Assessments of Non-Oncology Rare Disease Therapies. [PDF]

J Mark Access Health Policy
Blandy O, Lembo P, Folorunso R, Myren KJ, Chevrou-Severac H, Thomas SK.   +5 more
europepmc   +1 more source

Model‐Agnostic Influential Outlier Metric

Stat, Volume 15, Issue 3, September 2026.
ABSTRACT The influential outlier metric (IOM) provides model‐agnostic influential outlier detection. We define influence of an observation using a combination of SHapley Additive exPlanation (SHAP) values and the residual. Both are transformed using normalizing flows, changing their respective measures to Gaussian distributions.
Colin C. Jones, David A. Campbell
wiley   +1 more source

Long‐Term Safety and Efficacy of Efgartigimod PH20 in Chronic Inflammatory Demyelinating Polyradiculoneuropathy: ADHERE/ADHERE+ Trial Interim Analysis

Journal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT Background and Aims In ADHERE, subcutaneous efgartigimod PH20 (1000 mg once weekly) was effective and well tolerated in participants with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). ADHERE+ is an open‐label extension of ADHERE assessing long‐term safety and efficacy. Methods Eligible participants from ADHERE run‐in period
Jeffrey A. Allen, Geoffrey Istas, Satoshi Kuwabara, Trevor Mole, Luis Querol, Simon Rinaldi, Mark Stettner, Benjamin Van Hoorick, Richard A. Lewis   +8 more
wiley   +1 more source

From molecular networks to translational intervention: current progress in the mechanisms of gemcitabine resistance in bladder cancer. [PDF]

Front Immunol
Jin M, Cai Z, Bu M, Liu J, Zhang X.
europepmc   +1 more source

This is fine: Mule deer and elk do not substantially change their behavior in response to active wildfires

The Journal of Wildlife Management, Volume 90, Issue 6, August 2026.
During an outbreak of 7 wildfires in eastern Oregon, USA, we analyzed the home range and movement patterns of mule deer and elk before, during, and immediately after wildfires. Mule deer maintained high site fidelity during the wildfire but used their home range more uniformly and had higher daily displacement than deer unaffected by wildfire.
Jacob W. Dittel, Darren A. Clark
wiley   +1 more source

Unsupervised cross domain adaptive anomaly detection network for Internet of Things traffic. [PDF]

PLoS One
Yuan T, Zhai D, Li A.
europepmc   +1 more source