Results 191 to 200 of about 10,635 (224)
Codanin‐1, mutated in the anaemic disease CDAI, regulates Asf1 function in S‐phase histone supply
Efficient supply of new histones during DNA replication is critical to restore chromatin organization and maintain genome function. The histone chaperone anti-silencing function 1 (Asf1) serves a key function in providing H3.1-H4 to CAF-1 for replication-
Genevieve Almouzni +2 more
exaly +2 more sources
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CDAI and DAS28 in the management of rheumatoid arthritis in clinical practice
Annals of the Rheumatic Diseases, 2020The primary therapeutic target for rheumatoid arthritis is remission, assessed using validated composited measures.1 Currently, index-based remission frequently used in clinical practice are disease activity (CDAI) and Disease Activity Score for 28 joints (DAS28).
Satoshi Takanashi +2 more
exaly +3 more sources
Short CDAI: Development and validation of a shortened and simplified Crohnʼs disease activity index
Inflammatory Bowel Diseases, 2011The aim of this study was to develop a shortened Crohn's Disease Activity Index (CDAI).A short CDAI was developed retrospectively using patient-level data from four budesonide clinical trials to select variables from the full CDAI which best predicted health-related quality of life as measured by the Inflammatory Bowel Disease Questionnaire (IBDQ ...
Edward Loftus, Tore Persson
exaly +3 more sources
Definition of rheumatoid arthritis flare based on SDAI and CDAI
To develop and validate definitions for disease flares in rheumatoid arthritis (RA) based on the quantitative Simplified and Clinical Disease Activity Indices (SDAI, CDAI).We analysed RA treatment courses from the Norwegian disease-modifying antirheumatic drug registry (NOR-DMARD) and the Vienna RA cohort.
Sella Aarrestad Provan +2 more
exaly +3 more sources
Rheumatology International, 2011
To investigate the clinical results of 1 year tocilizumab (TCZ) treatment of rheumatoid arthritis patients in clinical practice by using the clinical disease activity index (CDAI). Thirty-one patients with inadequate response to DMARDs, including methotrexate (MTX), or TNF inhibitors received TCZ (8 mg every 4 weeks).
Atsushi, Kaneko +4 more
exaly +3 more sources
To investigate the clinical results of 1 year tocilizumab (TCZ) treatment of rheumatoid arthritis patients in clinical practice by using the clinical disease activity index (CDAI). Thirty-one patients with inadequate response to DMARDs, including methotrexate (MTX), or TNF inhibitors received TCZ (8 mg every 4 weeks).
Atsushi, Kaneko +4 more
exaly +3 more sources
Scores for all seasons: SDAI and CDAI.
Clinical and experimental rheumatology, 2014Disease activity assessment is one of the most pivotal aspects in the care of RA patients. Composite measures of disease activity are superior to individual measures, since they capture the multiple facets of the disease. Since swollen joint counts correlate with joint damage progression and tender joint counts with physical function, composite scores ...
J S, Smolen, D, Aletaha
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Efficacy of tocilizumab and evaluation of clinical remission as determined by CDAI and MMP-3 level
Modern Rheumatology, 2009Tocilizumab, a biological agent developed in Japan, is a human anti-interleukin-6 (anti-IL-6) receptor antibody. Rheumatoid arthritis improves with its use. A remission rate of 59% is attainable, as measured by disease activity score 28 (DAS28) in the SAMURAI study.
Keiko, Funahashi +5 more
openaire +2 more sources
Information technology concerning SDAI and CDAI.
Clinical and experimental rheumatology, 2017Disease activity assessment of rheumatoid arthritis has never been trivial. Composite indices like the Disease Activity Score using 28 joint counts 28 (DAS28) and the Clinical Disease Activity Index (CDAI) and the Simplified Disease Activity Index (SDAI) attempted to integrate several core set variables into one readout, which eventually laid the ...
Daniel, Aletaha +2 more
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AB0233 ATTAINING CDAI REMISSION IS THE FIRST GATEWAY TO ATTAIN BOOLEAN REMISSION
Annals of the Rheumatic Diseases, 2020Background: Boolean remission is most stringent but most comparable remission status for the patient with rheumatoid arthritis (RA). Clinical remission evaluated with clinical disease activity index (CDAI) is also one of the most popular index for evaluation of RA treatment. These two criteria often overlap, but some are split.
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THU0344 DAS-28, SDAI and CDAI in the patients with rheumatoid arthritis and concomitant fibromyalgia
Annals of the Rheumatic Diseases, 2012Background Composite indices DAS-28 (Disease Activity Score, assessing 28 joints), SDAI (Simplified Disease Activity Index), CDAI (Clinical Disease Activity Index) are widely used instruments for the assessment of disease activity in the patients (pts) with rheumatoid arthritis (RA), but they may not be sufficient to evaluate activity in cases of RA ...
J. Toms, P. Bradna, T. Soukup, Z. Hrncir
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