Results 241 to 250 of about 20,775 (267)

Balancing Efficiency and Equity in Population-Wide CKD Screening.

JAMA Netw Open
Cusick MM, Tisdale RL, Adams AS, Chertow GM, Owens DK, Salomon JA, Goldhaber-Fiebert JD.   +6 more
europepmc   +1 more source

Six Drivers of Aging Identified Among Genes Differentially Expressed With Age. [PDF]

Aging Cell
Coler-Reilly A, Pincus Z, Scheller EL, Civitelli R.   +3 more
europepmc   +1 more source

Integrated transcriptomic and immunoinformatics analysis identifies tpx2, bub1b, and ube2c as diagnostic biomarkers and therapeutic targets in endometrial carcinoma. [PDF]

Discov Oncol
Zhou S, Sun J, Li J, Zhou X, Shi X, Yang M, Wang Y, Zhang J.   +7 more
europepmc   +1 more source

Statistical and machine learning based platform-independent key genes identification for hepatocellular carcinoma. [PDF]

PLoS One
Hasan MAM, Maniruzzaman M, Huang J, Shin J.   +3 more
europepmc   +1 more source

Small Molecules Identified by an In Silico Docking Screen Targeting Anaphase-Promoting Complex/Cyclosome Subunit 1 (APC1) Potentiate Paclitaxel-Induced Breast Cancer Cell Death. [PDF]

Molecules
Schuyler SC, Gupta R, Nguyen TTB, Weng CY, Chen HY.   +4 more
europepmc   +1 more source

Integrated analysis of microRNA and mRNA interactions regulating fecundity in the ovaries of two distinct sheep breeds. [PDF]

BMC Genomics
Yousuf S, Malik WA, Feng H, Liu T, Xie L, Miao X.   +5 more
europepmc   +1 more source

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Targeting Cdc20 for cancer therapy.

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2022
The Anaphase-Promoting Complex/Cyclosome (APC/C), an E3 ubiquitin ligase, and two co-activators, Cdc20 and Cdh1, enable the ubiquitin-dependent proteasomal degradation of various critical cell cycle regulators and govern cell division in a timely and precise manner.
S. Jeong, Q. Bui, Minseok Kwak, Ji Yeon Lee, P. C. Lee   +4 more
semanticscholar   +3 more sources

Current progress and perspectives of CDC20 in female reproductive cancers.

Current Molecular Medicine, 2022
The cancers of cervix, endometrium, ovary and breast are great threats to women's health. Cancer is characterized by the uncontrolled proliferation of cells and deregulated cell cycle progression is one of the main causes of malignancy.
K. Ni, L. Hong
semanticscholar   +3 more sources

Enhancing Bone Regeneration through CDC20‐Loaded ZIF‐8 Nanoparticles Wrapped in Erythrocyte Membranes with Targeting Aptamer

Advanced Healthcare Materials, 2023
In the context of bone regeneration, nanoparticles harboring osteogenic factors have emerged as pivotal agents for modulating the differentiation fate of stem cells.
Yangge Du, Tian Deng, Yihong Cheng, Qin Zhao, Haibin Xia, Yaoting Ji, Yufeng Zhang, Qing He   +7 more
semanticscholar   +1 more source

Leishmania express a functional Cdc20 homologue

Biochemical and Biophysical Research Communications, 2011
Our knowledge concerning the mechanisms of cell cycle regulation in organisms belonging to the Trypanosometidae family is limited. Leishmania donovani are parasitic protozoa that cause kala azar, a fatal form of visceral leishmaniasis in humans. Here we provide evidence that the L. donovani genome contains a Cdc20 homologue. Cdc20 is a regulator of the
Listovsky, Tamar, Brandeis, Michael, Zilberstein, Dan   +2 more
openaire   +2 more sources