Results 231 to 240 of about 211,299 (317)

Cost Data Management System (CDMS). User's guide. CDMS Version 1. 1

, 1984
J.M. Weingart
openalex   +2 more sources

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, Volume 13, Issue 8, 9 February 2026.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Breaking data silos: incorporating the DICOM imaging standard into the OMOP CDM to enable multimodal research. [PDF]

J Am Med Inform Assoc
Park WY, Sippel Schmidt T, Salvador G, O'Donnell K, Genereaux B, Jeon K, You SC, Dewey BE, Nagy P, Alzheimer’s Disease Neuroimaging Initiative .   +9 more
europepmc   +1 more source

Action of Betulinic Acid in the Inhibition of Efflux Pump NorA in Staphylococcus aureus Strains: In Vitro and In Silico Approaches

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT Antibiotic resistance poses a serious challenge to public health, particularly in the case of Staphylococcus aureus, a Gram‐positive bacterium that employs multiple resistance mechanisms, including efflux pumps such as NorA, which extrude antimicrobial compounds from the cell and reduce antibiotic efficacy. Therefore, the search for substances
Camila Aparecida Pereira da Silva, Nara juliana Santos Araujo, Cícera Datiane Morais Oliveira‐Tintino, José Maria Barbosa Filho, Gabriel Gonçalves Alencar, José Bezerra de Araújo‐Neto, Josefa Sayonara dos Santos, Juliete Bezerra Soares, Carolina Bandeira Domiciano, Henrique Douglas Melo Coutinho, Jacqueline Cosmo Andrade‐Pinheiro   +10 more
wiley   +1 more source

DEUS Full Observable {\Lambda}CDM Universe Simulation: the numerical challenge

, 2020
Jean‐Michel Alimi, Vincent Bouillot, Yann Rasera, Vincent Reverdy, Pier-Stefano Corasaniti, Irène Balmès, Stéphane Requena, Xavier Delaruelle, Jean-Noel Richet   +8 more
openalex   +1 more source

Model‐Informed Drug Development for Daprodustat Supports the Design of Individualized Dosing Regimens in Chronic Kidney Disease Patients With Anemia

Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 322-335, February 2026.
Model‐informed drug development (MIDD) played a crucial role in the successful development and regulatory approval of daprodustat, a novel oral hypoxia‐inducible factor prolyl hydroxylase (HIF‐PHI) inhibitor aimed at treating anemia in chronic kidney disease patients.
Kelly M. Mahar, Shuying Yang, Brendan Johnson, Sandra A.G. Visser, Paul van den Berg, Martijn van Noort, Teun M. Post   +6 more
wiley   +1 more source

Enhancing cyberthreat defense mechanisms using ensemble of representation learning with binary Ebola optimization search in internet of things environment. [PDF]

Sci Rep
Alanazi MH, Alkhateeb JH, Alamro H, Asiri MM, Alahmari S, Alqazzaz A, Alshuhail A, Alkhiri H.   +7 more
europepmc   +1 more source

Survival of Intravenous Edaravone–Treated Patients With ALS: Evidence From Administrative Claims Analyses

Muscle &Nerve, Volume 73, Issue S1, Page S23-S25, February 2026.
ABSTRACT Randomized controlled trials remain the cornerstone of evidence generation in amyotrophic lateral sclerosis (ALS), yet their inherent challenges, including disease rarity, heterogeneity, and limited validated biomarkers, highlight the need for complementary clinical evidence.
Benjamin Rix Brooks, James D. Berry, Malgorzata Ciepielewska   +2 more
wiley   +1 more source

Corpus Callosum Diffusion Restriction in Neonatal Congenital Myotonic Dystrophy. [PDF]

Cureus
Sakatani N, Ikeda H, Inami Y, Noguchi Y, Fujii K.   +4 more
europepmc   +1 more source