Baseline characteristics from evoke and evoke+: Two phase 3 randomized placebo-controlled trials of semaglutide in participants with early-stage symptomatic Alzheimer's disease. [PDF]
Scheltens P +10 more
europepmc +1 more source
Corporate Digital Responsibility (CDR)
Business decision-makers struggle to grasp the full extent of their actions and responsibilities regarding the benefits and externalities of digital technologies. A growing discussion on corporate digital responsibility (CDR) emerged, addressing the raised concerns and identifying opportunities.
Christ, Anna Sophia +2 more
openaire +1 more source
KRAS‐G12C: The neglected biomarker to detect patients with MUTYH‐associated polyposis
What's new? MUTYH‐associated polyposis is an underdiagnosed recessive syndrome that predisposes individual to colorectal cancer and frequently displays KRAS‐G12C mutations. By analyzing a large cohort of colorectal cancer patients routinely tested for KRAS, the authors assessed whether KRAS‐G12C detection could serve as a pre‐screening tool for the ...
Ana Beatriz Deleame Medeiros +9 more
wiley +1 more source
Healthful Plant-Based Diets and Cognitive Function in Older Adults: Mediation by Nutritional Status and Modification by Urban-Suburban Location and Gender in a Shanghai Community-Based Study. [PDF]
Huang Z +7 more
europepmc +1 more source
Abstract Objective To investigate discriminant validity and cost‐effectiveness of a stepwise case‐finding strategy for detecting dementia in Chinese community‐based audiovisual impairment population. Methods Data were derived from the Hangzhou Study and the China Health and Retirement Longitudinal Study (CHARLS).
Ting Pang +5 more
wiley +1 more source
Engineering Single-Chain Antibody Fragment (scFv) Variants Targeting A Disintegrin and Metalloproteinase-17 (ADAM-17). [PDF]
Kalantar M +5 more
europepmc +1 more source
Abstract INTRODUCTION Frontotemporal dementia (FTD) is the most common dementia in people under age 60. Although FTD is often characterized by behavioral symptoms, few national interventions address management of these symptoms. Here we describe our protocol for Support via Technology: Living and Learning with Advancing FTD (STELLA‐FTD), an ...
Allison Lindauer +7 more
wiley +1 more source
Biological effects of conventional and ultra high dose rate radiation in human cells. [PDF]
Ryan TL +13 more
europepmc +1 more source
Comparing the 5-year health state utility vale of cervical disc replacement and anterior cervical discectomy and fusion [PDF]
Brochin, Robert L +5 more
core +2 more sources
Band‐Selective IR PRESS for Brain Tumor Spectroscopy Allows Robust Detection of Lactate
Lactate quantification by MRS is hindered by lipid signal overlap at 1.3 ppm, frequently forcing the use of long echo times that suppress other metabolites. We developed SPIR‐PRESS, a selective inversion recovery technique that suppresses lipids while preserving metabolite sensitivity.
Shun Kishimoto +12 more
wiley +1 more source

