Results 91 to 100 of about 25,194 (214)
In this study, we conducted the first integrated pangenome and pan‐transcriptome analysis of the WOX gene family in alfalfa using 24 high‐quality accessions and 43 transcriptome datasets. Our results reveal strong evolutionary conservation dominated by core and soft‐core members, clade‐specific diversification driven mainly by dispersed duplication ...
Hao Wen +7 more
wiley +1 more source
ABSTRACT Background Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulnerable due to underdeveloped immune systems and immature physical barriers, a risk amplified by poor hygiene and limited healthcare access in low‐ and middle‐income countries (LMICs), leading to an ...
Alex Odoom +4 more
wiley +1 more source
Advancing treat-to-target in SLE: a pilot study using a clinical decision support system
Objective To evaluate the feasibility, usability and acceptability of implementing a treat-to-target (T2T) strategy supported by a Clinical Decision Support System (CDSS), in routine SLE outpatient care.Methods A 24-week, non-randomised, multicentre ...
Koen Vos +5 more
doaj +1 more source
Anaerobic biodegradation of benzene by sulphate‐reducing strain BzS1 was studied by combining genomics, differential proteomics and targeted metabolite analyses. Strain BzS1 has an exceptionally streamlined metabolism. A highly abundant heterotrimeric flavoprotein may add benzene to either enolpyruvate or glutaconyl‐CoA followed by channelling into the
Florin Musat +11 more
wiley +1 more source
Abstract Drug–drug interactions (DDIs) pose major risks in chronic disease management where polypharmacy is common. Although digital DDI tools are used widely to aid healthcare professionals, tools rely on theoretical interactions. This limitation questions their reliability and validity for clinical relevancy.
Brayden Ng Gibson +12 more
wiley +1 more source
Substance Use and Suicidality in People at Ultra‐High‐Risk of Psychosis: A Systematic Review
ABSTRACT Aim Substance use and suicidality are prevalent among individuals at ultra‐high‐risk (UHR) of psychosis, yet their relationship remains unclear. This systematic review synthesises evidence on the relationship between substance use and suicidality—comprising suicidal ideation, self‐harm, suicide attempts, and suicide deaths—in the UHR ...
Alicia Tan Jia Hui, Lee D. Mulligan
wiley +1 more source
Barley HvBODYGUARD1 controls cuticular specialisations regulated by SHINE transcription factors
Cuticle defects result from defective HvBDG1 alleles. Summary Land plants secrete a protective outer cuticular layer with diverse functions. Barley (Hordeum vulgare L.) develops two cuticular specialisations: the β‐diketone rich wax bloom on vegetative tissues and an adherent grain surface which sticks to the hulls, leading to barley's distinctive ...
Trisha McAllister +19 more
wiley +1 more source
BackgroundThe use of Clinical Decision Support Systems (CDSS), such as clinical decision rules, algorithms, or machine learning-based applications, has gained attention in recent years.
Collin JC Exmann +19 more
doaj +1 more source
ABSTRACT Anthracnose caused by Colletotrichum gloeosporioides is a major threat to tea cultivation; however, the molecular mechanism underlying different resistance among tea cultivars remains unclear. We identified distinct expression patterns of CsMYB82 between anthracnose‐resistant and susceptible varieties after infection with anthracnose from ...
Rui Han +14 more
wiley +1 more source
Report containing the specific CDSS requirements to comply with the requirements and need defined in WP2. These specifications will also contain the anonymized data sets from EHRs.
openaire +1 more source

