Results 91 to 100 of about 25,194 (214)

Pangenome and Pan‐Transcriptome Analysis of the WOX Gene Family Reveals Evolutionary Conservation and Diversification in Alfalfa

open access: yesEcology and Evolution, Volume 16, Issue 8, August 2026.
In this study, we conducted the first integrated pangenome and pan‐transcriptome analysis of the WOX gene family in alfalfa using 24 high‐quality accessions and 43 transcriptome datasets. Our results reveal strong evolutionary conservation dominated by core and soft‐core members, clade‐specific diversification driven mainly by dispersed duplication ...
Hao Wen   +7 more
wiley   +1 more source

Neonatal Bloodstream Infections: A Narrative Review on Diagnostic and Therapeutic Challenges and Prospects in Developing Countries

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Bloodstream infections (BSIs) pose a significant global health challenge, particularly in developing countries. Neonates are highly vulnerable due to underdeveloped immune systems and immature physical barriers, a risk amplified by poor hygiene and limited healthcare access in low‐ and middle‐income countries (LMICs), leading to an ...
Alex Odoom   +4 more
wiley   +1 more source

Advancing treat-to-target in SLE: a pilot study using a clinical decision support system

open access: yesLupus Science and Medicine
Objective To evaluate the feasibility, usability and acceptability of implementing a treat-to-target (T2T) strategy supported by a Clinical Decision Support System (CDSS), in routine SLE outpatient care.Methods A 24-week, non-randomised, multicentre ...
Koen Vos   +5 more
doaj   +1 more source

Putative Mechanisms for Initial Reaction of Anaerobic Benzene Degradation Presumably Involving a Flavoprotein

open access: yesEnvironmental Microbiology, Volume 28, Issue 8, August 2026.
Anaerobic biodegradation of benzene by sulphate‐reducing strain BzS1 was studied by combining genomics, differential proteomics and targeted metabolite analyses. Strain BzS1 has an exceptionally streamlined metabolism. A highly abundant heterotrimeric flavoprotein may add benzene to either enolpyruvate or glutaconyl‐CoA followed by channelling into the
Florin Musat   +11 more
wiley   +1 more source

Identification, reliability, and validity of drug–drug interaction checkers in chronic diseases: A systematic review

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 16, Page 4532-4561, August 2026.
Abstract Drug–drug interactions (DDIs) pose major risks in chronic disease management where polypharmacy is common. Although digital DDI tools are used widely to aid healthcare professionals, tools rely on theoretical interactions. This limitation questions their reliability and validity for clinical relevancy.
Brayden Ng Gibson   +12 more
wiley   +1 more source

Substance Use and Suicidality in People at Ultra‐High‐Risk of Psychosis: A Systematic Review

open access: yesEarly Intervention in Psychiatry, Volume 20, Issue 8, August 2026.
ABSTRACT Aim Substance use and suicidality are prevalent among individuals at ultra‐high‐risk (UHR) of psychosis, yet their relationship remains unclear. This systematic review synthesises evidence on the relationship between substance use and suicidality—comprising suicidal ideation, self‐harm, suicide attempts, and suicide deaths—in the UHR ...
Alicia Tan Jia Hui, Lee D. Mulligan
wiley   +1 more source

Barley HvBODYGUARD1 controls cuticular specialisations regulated by SHINE transcription factors

open access: yesNew Phytologist, Volume 251, Issue 3, Page 1188-1208, August 2026.
Cuticle defects result from defective HvBDG1 alleles. Summary Land plants secrete a protective outer cuticular layer with diverse functions. Barley (Hordeum vulgare L.) develops two cuticular specialisations: the β‐diketone rich wax bloom on vegetative tissues and an adherent grain surface which sticks to the hulls, leading to barley's distinctive ...
Trisha McAllister   +19 more
wiley   +1 more source

Uptake of Clinical Decision Support Systems Among Health Care Professionals in Six European Countries and the United States: Cross-Sectional Survey Within the I-CARE4OLD Project

open access: yesJournal of Medical Internet Research
BackgroundThe use of Clinical Decision Support Systems (CDSS), such as clinical decision rules, algorithms, or machine learning-based applications, has gained attention in recent years.
Collin JC Exmann   +19 more
doaj   +1 more source

Regulatory Mechanism of CsMYB1‐CsMYB82/CsbHLH48‑CsCAD4 Model for Resistance Against Colletotrichum gloeosporioides in Camellia sinensis

open access: yesPlant Biotechnology Journal, Volume 24, Issue 8, Page 4725-4747, August 2026.
ABSTRACT Anthracnose caused by Colletotrichum gloeosporioides is a major threat to tea cultivation; however, the molecular mechanism underlying different resistance among tea cultivars remains unclear. We identified distinct expression patterns of CsMYB82 between anthracnose‐resistant and susceptible varieties after infection with anthracnose from ...
Rui Han   +14 more
wiley   +1 more source

CDSS requirements

open access: yes
Report containing the specific CDSS requirements to comply with the requirements and need defined in WP2. These specifications will also contain the anonymized data sets from EHRs.
openaire   +1 more source

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