Physics-Informed Artificial Intelligence Design of Picomolar Nanobodies Enables Deep Tumor Penetration and High-Contrast Imaging. [PDF]
Shi N +19 more
europepmc +1 more source
A Cyclic {NiII8DyIII4} Cluster Where the DyIII Moments Are Organized by the Transition Metal Spins
The synthesis, structural characterisation, and magnetic properties of a cyclic Ni8Dy4 coordination cluster are reported. Ab initio CASSCF and DFT calculations help rationalize the shape of the microSQUID hysteresis and the competing magnetic interactions within the compound. ABSTRACT A series of [Ni8Ln4(CO3)4(L)8(NO3)2(H2O)8 (MeOH)4](NO3)2 (Ln = Dy (1)
Imon J. Dutta +7 more
wiley +1 more source
Combined Detection of Preoperative Serum Calcitonin and Carcinoembryonic Antigen in Medullary Thyroid Carcinoma: A Retrospective Multicenter Cohort Study. [PDF]
Yang Y +22 more
europepmc +1 more source
When setting the price of cell and gene therapies in Japan, the factors considered include the manufacturing and operating costs of the new drug or a comparator, leading to discrepancies between price and values, in particular those specific to cell and gene therapies.
Akina Takami, Ataru Igarashi
wiley +1 more source
Carcinoembryonic Antigen Flare Under Oxaliplatin-Based Chemotherapy Predicts Benefit from Nivolumab in Metastatic Microsatellite-Stable Colorectal Cancer - A Post Hoc Analysis of METIMMOX Trial Data. [PDF]
Meltzer S +10 more
europepmc +1 more source
This review systematically examines how different transition metal compounds—such as binary and multinary metal oxides, halides, sulfides, and salts—exhibit thermochromism based on the d‐electron configurations of their transition metal cations. It focuses on three main mechanisms of thermochromism: phase transition, charge transfer, and bandgap change.
Jie Wang +5 more
wiley +1 more source
Survival prediction in stage II/III rectal cancer: Role of immune-inflammatory biomarkers post neoadjuvant chemoradiotherapy. [PDF]
Li B +6 more
europepmc +1 more source
Abstract Objective This study was undertaken to design and validate a hybrid depth electrode combining stereoelectroencephalographic (sEEG) recording and magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) under real‐time magnetic resonance thermometry, to streamline the transition from invasive localization to focal ablation in ...
Bertrand Mathon +3 more
wiley +1 more source
Challenges in Implementing Revocation of Oncology Drugs Under Conditional Early Approval in Japan: Regulatory Insights From Comparisons With FDA/EMA. [PDF]
Handa T, Tanaka A, Shikano M, Wakao R.
europepmc +1 more source
ABSTRACT Earthquake‐induced damage of structures can trigger cascading hazards, linking structural performance to nonstructural consequences. In current engineering practice, these two aspects are typically addressed separately, limiting the ability to account for such coupled effects in design.
Matjaž Dolšek +2 more
wiley +1 more source

