Results 261 to 270 of about 44,409 (342)

Microbiota-host crosstalk: the role of short-term dietary restriction in neurological and metabolic dysregulation. [PDF]

NPJ Biofilms Microbiomes
Li Y, Chen J, Qi X, He Y, Wang G, Wei L, Hong W.   +6 more
europepmc   +1 more source

Feedback regulation between histone H3 lysine 18 lactylation and TROP2‐mediated glycolysis drives metastatic progression of colorectal cancer

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
TROP2 is upregulated in CRC metastasis and promotes lactate overproduction via YBX1‐HIF‐1α signalling. TROP2 signalling induces H3K18la at metastasis genes promoters in CRC and promotes their expression. AccLactate sustains TROP2 expression in CRC cells via H3K18la Acriflavine suppresses TROP2‐driven CRLM by targeting the H3K18la/TROP2 feedback loop ...
Weifeng Wang, Yuxiang Deng, Weihao Li, Ruowei Wang, Chi Zhou, Yanbo Xu, Jiahua He, Le' en Liao, Jin Lan, Long Yu, Da Kang, Weili Zhang, Qingjian Ou, Zhizhong Pan, Yujing Fang, Peirong Ding, Junzhong Lin, Jianhong Peng   +17 more
wiley   +1 more source

Compound Probiotics Enhance Performance, Antioxidant Status, and Cecal SCFAs in Post-Molting Broiler Breeders. [PDF]

Animals (Basel)
Yang B, Wei Y, Yang Y, Zhang M, Wang C, Wang Q, Wang J, Wang X, Fan B.   +8 more
europepmc   +1 more source

Targeting the lactylation of ENO1 alleviates endothelial dysfunction in sepsis

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Lactylation of ENO1 reduced the binding of TRIM21 mRNA to ENO1, thereby preventing mRNA degradation. Elevated TRIM21 subsequently binds to VE‐Cadherin, promoting its ubiquitination. Targeting the lactylation of ENO1 with a specific inhibitory peptide alleviated endothelial dysfunction.
Xueru Xie, Tingyan Liu, Caiyan Zhang, Ye Cheng, Yajing Gao, Wenfeng Xiao, Haiyan Guo, Yutong Zhou, Yawei Yu, Kexin Wang, Yinghong Lin, Lisheng Xiao, Yingying Zhang, Weiguo Yang, Gangfeng Yan, Guoping Lu, Yufeng Zhou   +16 more
wiley   +1 more source

Effects of <i>Zanthoxylum bungeanum</i> Leaves on Production Performance, Egg Quality, Antioxidant Status, and Gut Health in Laying Hens. [PDF]

Animals (Basel)
Lei Q, Li X, Cao S, Zhao J, Liu J.
europepmc   +1 more source

DSOK‐0011 Potentially Regulates Circadian Misalignment and Affects Gut Microbiota Composition in Activity‐Based Anorexia Model

International Journal of Eating Disorders, Volume 59, Issue 1, Page 54-69, January 2026.
ABSTRACT Objective Anorexia nervosa (AN) is a metabolic‐psychiatric disorder characterized by severe weight loss, hypercortisolemia, and hypothalamic–pituitary–adrenal (HPA) axis activation. In this study, we investigated the effect of inhibiting cortisol regeneration via the enzyme 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1) on the ...
Hiroki Kawai, Nanami Wada, Shinji Sakamoto, Kenji Miyazaki, Taro Kato, Yoshihiro Horiuchi, Hiroshi Kirii, Hoang Duy Nguyen, Kenji Hinotsu, Yoshio Ohya, Takahiro Asada, Akiyoshi Yokode, Yuko Okahisa, Haruko Miyazaki, Toshitaka Oohashi, Manabu Takaki   +15 more
wiley   +1 more source

Long-Term Immunogenicity and Protection of a rHVT-H9/Y280 Vaccine Against H9N2 Avian Influenza Virus in Commercial Layers with High Maternal Antibodies. [PDF]

Animals (Basel)
Kim SW, Park JY, Son JE, Zheng KQ, Yu CD, Kim KW, Jeon WB, Choi YR, Jang HK, Wei B, Kang M.   +10 more
europepmc   +1 more source

Renoprotective Effect of Coix lachryma‐jobi L. Seed Polysaccharides in Adenine‐Induced Chronic Renal Failure by Blocking Gut Urea Metabolism

Food Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT Dietary soluble fiber may alleviate renal damage in chronic kidney disease (CKD) by promoting intestinal urea excretion, though the underlying mechanisms remain unclear. This study investigated the digestion, fermentation, and renoprotective effects of Coix lachryma‐jobi L.
Hongmei Yin, Wanjun Liao, Yilian Huang, Qiang Hong, Na Zhang, Xiaodan Shi, Zongcai Tu, Hui Wang, Zuohua Xie, Tao Yuan   +9 more
wiley   +1 more source

Maternal obesogenic diet exposure regulates the offspring gut liver axis and fibroinflammatory liver disease. [PDF]

Commun Biol
Ramavath NN, Özler O, Hinrichs H, Victorino FR, Lian V, Young M, Bigley TM, Thompson MD.   +7 more
europepmc   +1 more source

Cyclophosphamide for clinical renal and hepatic transplantation. [PDF]

, 1973
Cascardo, S, Corman, J, Geis, P, Groth, CG, Gustafsson, A, Halgrimson, CG, Husberg, B, Iwatsuki, S, Penn, I, Putnam, CW, Starzl, TE   +10 more
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