Results 261 to 270 of about 2,157,209 (306)

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

open access: yesExperimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris   +10 more
wiley   +1 more source

Translating gut microbiome research into therapies for type 1 diabetes

open access: yesExperimental Physiology, EarlyView.
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok   +2 more
wiley   +1 more source

Peripheral non‐invasive focused ultrasound alleviates constipation by reducing gastrointestinal inflammation

open access: yesExperimental Physiology, EarlyView.
Abstract Constipation affects approximately 20% of the US population, with diverse treatment options available due to the unclear onset and causes of the condition. Recently, focused ultrasound (FUS) has been proposed as a novel, non‐invasive peripheral neuromodulatory treatment that may reduce this inflammation.
Dia Shah   +11 more
wiley   +1 more source

Acidification-dependent suppression of <i>C. difficile</i> by pathogenic and commensal enterococci. [PDF]

open access: yesInfect Immun
Neubauer HR   +8 more
europepmc   +1 more source

Prepackaged Low‐Residue Diet “Clear‐Through” Reduces the Required Volume of Polyethylene Glycol Solution for Colonoscopy Preparation: An Exploratory Randomized Controlled Study

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Large volumes of polyethylene glycol (PEG) solution reduce patient acceptance of colonoscopy. A prepackaged low‐residue diet (PLRD; Clear‐Through) may improve bowel cleansing and allow further PEG reduction. This exploratory randomized study evaluated whether PLRD permits decreased PEG with ascorbic acid (PEG‐Asc) volume while ...
Toshifumi Iida   +16 more
wiley   +1 more source

Targeting microbial bile salt hydrolase reprograms bile acid metabolism and ameliorates metabolic dysfunction-associated steatohepatitis in mice. [PDF]

open access: yesMol Metab
Wei W   +17 more
europepmc   +1 more source

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