Results 31 to 40 of about 101,486 (217)

Delayed Diagnosis of Lynch Syndrome in a 76-Year-Old Man with Metachronous Colon Cancer

Journal of Hospital General Medicine
Lynch syndrome increases the lifetime risk of colorectal and endometrial malignancies. Herein, we present the case of a 76-year-old man with sigmoid colon cancer with delayed Lynch syndrome diagnosis.
Takayuki Yamada, Susumu Ohwada, Yohei Miyamae   +2 more
doaj   +1 more source

Rare neoplasms

, 2014
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
Valentina Ciaravino, CIARAVINO, VALENTINA, Roberto Malagò, MALAGO', Roberto, Roberto Pozzi Mucelli, Capelli, Paola, Paola Capelli, DE ROBERTIS LOMBARDI, Riccardo, PEDICA, Federica, Riccardo De Robertis, Federica Pedica, POZZI MUCELLI, Roberto   +11 more
core   +1 more source

Neuroendocrine Neoplasms

, 2022
Pancreatic neuroendocrine neoplasms (PanNENs) are tumors with neuroendocrine differentiation and are divided into functioning (syndromic) or non-functioning based on the clinical syndromes. Insulinomas are the most common functioning NETs.
Maria Gaia Mastrosimini, Lavinia Stefanizzi, Stefano Gobbo, Paola Capelli, Paolo Tinazzi Martini, Aldo Scarpa, Mirko D’Onofrio, Riccardo De Robertis, Alessandro Beleù, Luca Geraci   +9 more
core   +1 more source

Advanced Imaging of Pancreatic Neoplasms

, 2022
Imaging has a pivotal role in pancreatic neoplasms, ranging from diagnosis to treatment monitor. It is crucial, especially for pancreatic ductal adenocarcinoma (PDAC), to obtain an early diagnosis, since the therapeutic approach is mainly surgical and ...
Cardobi N., De Robertis R., D'Onofrio M.
core   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Cecal Volvulus: Report of a Case [PDF]

, 2009
A rare case of cecal volvulus that was preoperatively diagnosed and surgically treated is herein reported. An 85-year-old woman was admitted to our hospital because of abdominal pain and distension concomitant with nausea and vomiting.
Murakami, Goushi, Nakahara, Nobuya, Kondo, Masamichi, Nakagoe, Tohru, Shimokawa, Isao, Matsuo, Toshikazu, Ohara, Hiroshi, Nakamura, Shiro   +7 more
core  

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Low-Grade Appendiceal Mucinous Neoplasms: Description of Two Cases and Literature Review

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to present two clinical cases of low-grade appendiceal mucinous neoplasms (LAMN) and evaluate the oncological adequacy of ileocecectomy with ileoascending anastomosis in patients with cecal involvement.Key points.
R. Bayramov, H. Muradov, S. Huseynova, Z. Maharramov, F. Bayramli, F. Ibrahimova   +5 more
doaj   +1 more source

Mucinous Neoplasms

, 2014
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
D'ONOFRIO, Mirko, Paolo Tinazzi Martini, Giovanni Morana, Crosara, Stefano, Riccardo De Robertis, Emilio Barbi, Capelli, Paola, MORANA, Giovanni, Paola Capelli, DE ROBERTIS LOMBARDI, Riccardo, Barbi, Emilio, TINAZZI MARTINI, Paolo, LUCHINI, Claudio, Mirko D’Onofrio, Claudio Luchini, Stefano Crosara   +15 more
core   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source