Results 61 to 70 of about 6,572 (187)

Capsule Endoscopy in Inflammatory Bowel Disease: Current Status and Issues in Clinical Practice

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Inflammatory bowel diseases include Crohn's disease (CD) and ulcerative colitis (UC), both of which require endoscopic evaluation of mucosal surfaces. Capsule endoscopy has been used in clinical practice since 2000 as a minimally invasive means of mucosal evaluation.
Teppei Omori, Haruka Wada, Tatsuya Mitsui, Mari Hayashida, Noritaka Hibi, Daisuke Saito, Tadakazu Hisamatsu   +6 more
wiley   +1 more source

Successful Endoscopic Submucosal Dissection for Giant Inflammatory Fibroid Polyp in Terminal Ileum

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT A 55‐year‐old woman presented with postprandial abdominal pain and diarrhea. Contrast‐enhanced abdominal computed tomography revealed a large tumor in the ileocecal region. Colonoscopy demonstrated a pedunculated polyp originating from the terminal ileum, intermittently prolapsing into the cecum with a stalk‐like base.
Sayuri Watanabe, Yuki Nakajima, Masato Aizawa, Jun Wada, Kakeru Otomo, Goro Shibukawa, Tadayuki Takagi, Kenichi Utano, Osamu Suzuki, Kazutomo Togashi   +9 more
wiley   +1 more source

Successful Colonic Stenting Across the Ileocecal Valve With Severe Malignant Stenosis Using Ultra‐thin Scope and Single‐balloon Overtube

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Self‐expanding metallic stents (SEMSs) are an established palliative option for malignant colonic obstruction, including in cases with proximal lesions. However, SEMS placement across the ileocecal valve (ICV) can be technically challenging because of the anatomical curvature and luminal stenosis. Herein, we report a successful case of colonic
Takato Maeda, Norihiro Hanabata, Shohei Igarashi, Masayoshi Ko, Koji Shimaya, Hiroshi Numao, Masaki Munakata, Hirotake Sakuraba   +7 more
wiley   +1 more source

Gel‐immersion Endoscopic Submucosal Dissection for Superficial Colorectal Neoplasms: A Retrospective Study Comparing Conventional Endoscopic Submucosal Dissection

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Gel‐immersion endoscopy offers benefits such as buoyancy, traction, and a clear visual field without gas insufflation. While some case reports have described colorectal gel‐immersion endoscopic submucosal dissection (Gi‐ESD), there have been no consecutive case series. This study aimed to clarify the usefulness of Gi‐ESD.
Kenji Yamauchi, Tomoki Inaba, Takeshi Morimoto, Hugh Shunsuke Colvin, Akira Nakanishi, Shigenao Ishikawa, Masaki Wato   +6 more
wiley   +1 more source

Safety Profile of Low‐Power Pure‐Cut Hot Snare Polypectomy for 10–14 mm Nonpedunculated Colorectal Neoplasms

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives The reported rate of delayed bleeding (DB) after hot snare polypectomy (HSP) for 10–19‐mm polyps is 2.1%–2.8%, which is non‐negligible. We hypothesized that a low‐power pure‐cut current (LPPC) yields a lower risk of DB than a coagulation current, and we evaluated the safety of LPPC HSP for colorectal polyps.
Kazunori Takada, Hidenori Kimura, Kinichi Hotta, Kenichiro Imai, Sayo Ito, Yoshihiro Kishida, Noboru Kawata, Masao Yoshida, Yoichi Yamamoto, Tatsunori Minamide, Hirotoshi Ishiwatari, Junya Sato, Hiroyuki Matsubayashi, Hiroyuki Ono   +13 more
wiley   +1 more source

Comparison of Detection Yields Between Texture and Color Enhancement Imaging Mode 1 and Mode 2 for Colorectal Lesions: A Post‐hoc Analysis of a Multicenter Observational Study

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Colonoscopy is a reliable technique for the detection, diagnosis, and treatment of adenomas and early cancer. Image‐enhanced endoscopy (IEE) is important for detecting colorectal lesions. Texture and color‐enhancement imaging (TXI) has recently emerged as a novel modality for IEE.
Kensuke Shinmura, Hiroaki Ikematsu, Taku Sakamoto, Maasa Sasabe, Tatsuro Murano, Yasuhiko Mizuguchi, Hiroyuki Takamaru, Toshiki Futakuchi, Naoto Tamai, Kazuki Sumiyama, Yutaka Saito   +10 more
wiley   +1 more source

Preclinical Evaluation of the Safety of the Dedicated Gel for Gel Immersion Endoscopy With Gastrointestinal Perforation and Peritoneal Leakage

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Gel immersion endoscopic mucosal resection or endoscopic submucosal dissection has been developed as an alternative to saline immersion therapeutic endoscopy. However, in cases of gastrointestinal perforation, gel may leak from the lumen into the peritoneal cavity, and the safety of such events remains unclarified.
Atsushi Ohata, Ryo Kawahara, Yuji Hiraki, Hikaru Nakata, Shinya Kaneda, Tomonori Yano   +5 more
wiley   +1 more source

Adalimumab‐responsive Monogenic Inflammatory Bowel Disease With Pseudopolyposis Characteristic of TGFBR2 Variant in Loeys‐Dietz Syndrome

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Loeys‐Dietz syndrome (LDS) is an autosomal dominant connective tissue disorder caused by pathogenic variants in TGFBR1 or TGFBR2. It is characterized by vascular fragility, skeletal abnormalities, and predisposition to allergic and inflammatory conditions, including monogenic inflammatory bowel disease (IBD).
Tomomitsu Sado, Satoshi Ukai, Shingo Kurasawa, Yosuke Kono, Norio Hasuda, Mai Iwaya, Takaya Nakane, Tomomi Yamaguchi, Tomoki Kosho, Yoshiko Nakayama   +9 more
wiley   +1 more source

Feasibility Study of Modified Underwater Endoscopic Mucosal Resection for Colorectal Polyps

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Underwater endoscopic mucosal resection (UEMR) is widely performed for colorectal tumors. However, in our experience, it is sometimes difficult to keep a clear endoscopic view underwater, due to dirty fluid inflow or insufficient water pooling after grasping the polyp, or bleeding just after endoscopic resection.
Kaizo Kagemoto, Koichi Okamoto, Yoji Takeuchi, Yasuyuki Okada, Motoko Sei, Shota Fujimoto, Ryo Shinomiya, Takeshi Mitsuhashi, Takanori Yoshimoto, Reiko Yokoyama, Tomoyuki Kawaguchi, Yoshifumi Kida, Yasuhiro Mitsui, Yutaka Kawano, Masahiro Sogabe, Hiroshi Miyamoto, Yasushi Sato, Tetsuji Takayama   +17 more
wiley   +1 more source

Immunoglobulin G4‐Related Disease‐Like Gastric Lesion Presenting as Submucosal Tumor‐Like Lesions

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Immunoglobulin G4 (IgG4)‐related disease (RD) is a systemic fibroinflammatory condition characterized by infiltration of IgG4‐positive plasma cells (PCs). Gastrointestinal involvement may present as submucosal tumor–like lesions and poses diagnostic challenges.
Takayasu Kuroda, Kazuya Miyaguchi, Yoshikazu Tsuzuki, Hiroshi Yamaguchi, Hiroyuki Imaeda   +4 more
wiley   +1 more source