Women in space: A review of known physiological adaptations and health perspectives
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford +4 more
wiley +1 more source
TTSS-2 virulence drives inflammatory destruction of the gut epithelial barrier and modulates inflammatory response profiles in the Salmonella-infected mouse gut. [PDF]
Enz U +6 more
europepmc +1 more source
Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury
Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley +1 more source
Lactobacillus reuteri SKLAN202402ZF inhibited by early-life lincomycin exposure alleviate intestinal damage and inflammation sensitivity. [PDF]
Zhang S +8 more
europepmc +1 more source
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris +10 more
wiley +1 more source
Incidental Discovery and Removal of an Appendiceal Mucocele in a Patient With Acute Cholecystitis. [PDF]
Hunter H, Barber A, Samrao D.
europepmc +1 more source
Abstract Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide, traditionally studied as distinct pathologies. However, emerging evidence suggests a significant physiological and molecular overlap between these conditions, indicating that they might share common pathophysiological pathways. The
Mohamad Bashir +5 more
wiley +1 more source
Mechanisms of deoxynivalenol-induced multi-organ toxicity in broiler chickens: The central role of the Rap1/MAPK pathway revealed by network pharmacology and molecular docking. [PDF]
Zhuang C +6 more
europepmc +1 more source
Summary A 2‐month‐old Holstein bull calf presented with a 1‐week history of left front limb lameness. Lameness evaluation demonstrated a Grade 3/5 lameness in the left front limb. Clinical examination revealed resistance to flexion and extension of the left shoulder region, with no associated swelling or joint effusion.
Martina Ernestova, Sabrina H. Brounts
wiley +1 more source

