Results 121 to 130 of about 44,981 (233)

Time‐dependent wound management protocol prevents periprosthetic joint infection in total knee arthroplasty with persistent drainage

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 5, Page 1740-1749, May 2026.
Abstract Purpose This study aimed to evaluate the success rate of a standardised protocol for managing persistent wound drainage following total knee arthroplasty (TKA). Methods A prospective observational study was conducted at four institutions between January and June 2022 across primary and revision TKAs.
Filippo Leggieri   +8 more
wiley   +1 more source

Identification of a Novel De Novo Heterozygous SEC61A1 Variant in a Patient With Severe Congenital Neutropenia

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
Severe congenital neutropenia can be caused by rare SEC61A1 variants. We report a child with SCN showing granulocytic maturation arrest and abnormal immunophenotype, carrying a novel de novo SEC61A1 p.Trp379Arg variant, expanding the phenotypic and genetic spectrum of SEC61A1‐associated SCN.
Zixuan Wang   +4 more
wiley   +1 more source

Seropositive Rheumatoid Arthritis Emerging During Acute Phase of Lung Abscess: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 5, May 2026.
We report a rare case of seropositive rheumatoid arthritis (RA) that became clinically apparent during the acute phase of lung infection. This case demonstrates that RA can be diagnosed during the acute course of a respiratory infection and highlights the diagnostic value of rheumatoid factor and anti‐citrullinated protein antibodies testing when new ...
Yusuke Arai   +5 more
wiley   +1 more source

In vitro identification of underutilized β-lactam combinations against methicillin-resistant Staphylococcus aureus bacteremia isolates

open access: yesMicrobiology Spectrum
Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is a serious clinical challenge with high mortality rates. Antibiotic combination therapy is currently used in cases of persistent infection; however, the limited development of new ...
Kathleen P. Davis   +3 more
doaj   +1 more source

Isolation, Identification and Pathogenicity Analysis of Proteus mirabilis in Cynomolgus Monkey From Yunnan, China

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study demonstrated that the pathogen responsible for diarrhoea in a cynomolgus monkey was identified as Proteus mirabilis (P. mirabilis) through methods including bacterial isolation and culture, morphological examination, biochemical profiling, 16S rRNA sequencing, analysis of key virulence genes and bacterial artificial infection tests.
Heling Li   +6 more
wiley   +1 more source

Frequency of nasal colonization and antimicrobial resistance pattern of Methicillin susceptible and resistant Staphylococcus aureus strains among nursing staffs in a Teaching University Hospital, Ardabil - Iran [PDF]

open access: yes
Introduction & Objectives: Staphylococcus aureus is one of the most common causes of nosocomial infections. In many cases the bacterium is transmitted via nasal carrier healthcare providers or hospital environment.
احدی, پریسا   +5 more
core  

Pharmacokinetics of Flunixin and Tolfenamic Acid in Experimental Endotoxemic Awassi Sheep

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Endotoxemia was induced in the sheep in the group by administering 10 µg/kg of E. coli O55:B5 (LPS) toxin (via IV infusion in 30 mL of 0.9% NaCl over 30 min). The studies in the FM and TA groups were conducted according to a two‐stage crossover pharmacokinetic design, taking into account a 15‐day washout period between treatment periods ...
Fulya Altinok‐Yipel   +7 more
wiley   +1 more source

European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) 2025 guidelines for surgical antimicrobial prophylaxis in dogs and cats

open access: yesJournal of Small Animal Practice, Volume 67, Issue 5, Page 383-405, May 2026.
Surgical antimicrobial prophylaxis involves the administration of antimicrobials to reduce the risk of a surgical site infection and represents a significant proportion of all antimicrobial use in cats and dogs. This evidence‐based, European Network for Optimization of Veterinary Antimicrobial Therapy guideline provides recommendations for both peri ...
F. Allerton   +21 more
wiley   +1 more source

Adequate cefazolin therapy for critically ill patients: can we predict active concentrations from given protein-binding data?

open access: yesJournal of Laboratory Medicine
Therapeutic drug monitoring of β-lactam antibiotics has become an important tool for treatment of severe infections, especially for critically ill patients who often exhibit altered PK/PD.
Böhle Tony   +5 more
doaj   +1 more source

Exploring the Model of Cefazolin Released from Jellyfish Gelatin-Based Hydrogels as Affected by Glutaraldehyde

open access: yesGels
Due to its excellent biocompatibility and ease of biodegradation, jellyfish gelatin has gained attention as a hydrogel. However, hydrogel produced from jellyfish gelatin has not yet been sufficiently characterized.
Wiriya Charoenchokpanich   +7 more
doaj   +1 more source

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