Results 151 to 160 of about 5,449 (190)

Cefiderocol: A Siderophore Cephalosporin

Annals of Pharmacotherapy, 2020
Objective: This article reviews the available data on the chemistry, spectrum of activity, pharmacokinetic and pharmacodynamic properties, clinical efficacy, and potential place in therapy of cefiderocol. Data Sources: A literature ...
Rania M. El-Lababidi, John George Rizk
openaire   +2 more sources

Rapid cefiderocol NP test for detection of cefiderocol susceptibility/resistance in Enterobacterales

Journal of Antimicrobial Chemotherapy, 2022
Abstract Background Cefiderocol is among the latest generation of commercialized antibiotics against a large variety of MDR Gram-negative bacteria including carbapenem-resistant Enterobacterales and non-fermenters such as Pseudomonas aeruginosa and Acinetobacter baumannii.
Patrice Nordmann, Maxime Bouvier, Laurent Poirel, Mustafa Sadek   +3 more
openaire   +2 more sources

In a Pinch: Cefiderocol for CRAB Infections

Antimicrobial Agents and Chemotherapy, 2022
Carbapenem-resistant Acinetobacter baumannii (CRAB) can cause significant infections with limited treatment options available. Falcone et al. ( https://doi.org/10.1128/aac.02142-21 ) describe a single-center retrospective study comparing clinical outcomes among patients with CRAB infections ...
Sara M. Karaba, Elizabeth B. Hirsch, Emily L. Heil   +2 more
openaire   +2 more sources

Cefiderocol: a novel siderophore cephalosporin

Expert Opinion on Investigational Drugs, 2018
The emergence of multidrug-resistant bacterial pathogens has led to a global public health emergency and novel therapeutic options and drug-delivery systems are urgently needed. Cefiderocol is a siderophore cephalosporin antibiotic that has recently been developed to combat a variety of bacterial pathogens, including β-lactam- and carbapenem-resistant ...
Justin J, Choi, Matthew W, McCarthy
openaire   +2 more sources

Cefiderocol

Reactions Weekly, 2023
openaire   +2 more sources

A Drug Monograph; Cefiderocol

2023
Gün geçtikçe artan antibimikrobiyal direnç yeni antimikrobiyaller arayışını zorunlu kılmaktadır. Özellikle gram negatif bakterilerdeki karbapenem direnci endişe verici seviyelere ulaşmıştır ve güvenli alternatif tedavi seçeneklerinin olmaması nedeniyle küresel bir halk sağlığı sorunu haline gelmiştir.
KARS, Betül, ÖZTAŞ, Sevil, ALTINDİŞ, Mustafa   +2 more
openaire   +1 more source

Cefiderocol: Systematic Review of Mechanisms of Resistance, Heteroresistance and In Vivo Emergence of Resistance

Antibiotics, 2022
Stamatis Karakonstantis, Evangelos Kritsotakis   +1 more
exaly  

Disc Diffusion and ComASP® Cefiderocol Microdilution Panel to Overcome the Challenge of Cefiderocol Susceptibility Testing in Clinical Laboratory Routine

Antibiotics, 2023
Matteo Boattini, Rossana Cavallo, Cristina Costa   +2 more
exaly  

Mechanisms of Reduced Susceptibility to Cefiderocol Among Isolates from the CREDIBLE-CR and APEKS-NP Clinical Trials

Microbial Drug Resistance, 2022
Nordmann Patrice, Yohei Doi, Ryan Shields   +2 more
exaly  

Defining Baseline Mechanisms of Cefiderocol Resistance in the Enterobacterales

Microbial Drug Resistance, 2022
Patricia Simner, Pranita Tamma, Yehudit Bergman   +2 more
exaly