Results 1 to 10 of about 33,313 (208)

Role of SCCmec type in resistance to the synergistic activity of oxacillin and cefoxitin in MRSA

open access: yesScientific Reports, 2017
β-lactam antibiotics target penicillin-binding proteins (PBPs) preventing peptidoglycan synthesis and this inhibition is circumvented in methicillin resistant Staphylococcus aureus (MRSA) strains through the expression of an additional PBP, named PBP2A ...
Nathalie T Reichmann   +1 more
exaly   +3 more sources

Ceftaroline pharmacokinetics/pharmacodynamics in the hollow-fibre model of Mycobacterium abscessus lung disease [PDF]

open access: yesIJTLD Open
BACKGROUND: Guideline-based therapy (GBT) of Mycobacterium abscessus (MAB) lung disease (LD) achieves a sputum culture conversion rate in ∼35% of patients. The β-lactam antibiotics, imipenem and cefoxitin, are the cornerstone of GBT.
B.E. Ferro, S. Srivastava, T. Gumbo
doaj   +2 more sources

Should Cefoxitin Non-Susceptibility in Ceftriaxone-Susceptible E. coli and K. pneumoniae Prompt Concerns Regarding Plasmid-Mediated AmpC Resistance? A Genomic Characterization and Summary of Treatment Challenges in Singapore [PDF]

open access: yesAntibiotics
Objectives: Plasmid-mediated AmpC beta-lactamases represent a growing clinical concern in Enterobacterales, with challenges in diagnostic approaches, limited data on clinical outcomes, and our incomplete understanding of their regulatory mechanisms ...
Jonathan Jinpeng Foo   +8 more
doaj   +2 more sources

Nasal Carriage of Staphylococcus Aureus in Different Age Groups Among Healthy School Children and its Antimicrobial Susceptibility Pattern [PDF]

open access: yesNational Journal of Laboratory Medicine, 2021
Introduction: Staphylococcus aureus (S.aureus) is associated with increased risk for acquiring invasive disease. There exists an increasing prevalence of resistant community acquired S.aureus infections due to the nasal colonisation of S.aureus and ...
Dakshina Bisht, Varun Goel
doaj   +1 more source

Minimum Inhibitory Concentration of Vancomycin against Methicillin Resistant Staphylococcus aureus Strains Isolated from a Tertiary Care Hospital [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: Methicillin Resistant Staphylococcus aureus (MRSA) is one major healthcare associated infection. Prevalence of MRSA and its antibiotic susceptibility changes from time to time.
Subi Das, Prithi Nair Kannambra
doaj   +1 more source

Plasmid Derived AmpC Genotypes among the Multidrug Resistant Enterobacteriaceae Strains Isolated from Urine Samples in Southern India [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Introduction: The most common pathogens causing Urinary Tract Infections (UTI) in community and hospital settings are Enterobacteriaceae. Antibiotic resistance is a major problem worldwide because of an increase in the use of antibiotics.
P Ronni Mol   +2 more
doaj   +1 more source

Improved Detection of mecA-Mediated β-Lactam Resistance in Staphylococcus lugdunensis Using a New Oxacillin Salt Agar Screen

open access: yesFrontiers in Microbiology, 2021
Oxacillin resistance mediated by mecA in Staphylococcus lugdunensis is emerging in some geographic areas. We evaluated cefoxitin disk diffusion (DD) and a new oxacillin agar (supplemented with 2 μg/ml oxacillin and 2% sodium chloride) screen for the ...
Pak-Leung Ho   +10 more
doaj   +1 more source

Comparison of Different Phenotypic Methods of Detection of Methicillin-Resistant Staphylococcus aureus with Polymerase Chain Reaction

open access: yesJournal of Microbiology and Infectious Diseases, 2022
Objectives: The objective of the current study was to compare the diagnostic methods of Oxacillin Disk Diffusion, Cefoxitin Disk Diffusion, Oxacillin Resistance Screening Agar Base, and CHROM Agar MRSA with the gold-standard method of Polymerase Chain ...
Nupur Gupta   +3 more
doaj   +1 more source

Genomic characterization of oxacillin-susceptible mecA-positive Staphylococcus aureus ST59 [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2023
Objective. To characterize the genomes of oxacillin-susceptible mecA-positive Staphylococcus aureus ST59 isolated in St. Petersburg. Materials and Methods. Nine oxacillin-susceptible mecA-positive of S. aureus isolates (OS-MRSA) of ST59 were included
Gostev V.V.   +9 more
doaj   +1 more source

Integrated genome based evaluation of safety and probiotic characteristics of Lactiplantibacillus plantarum YW11 isolated from Tibetan kefir

open access: yesFrontiers in Microbiology, 2023
The comparative genomic analysis of Lactiplantibacillus plantarum YW11 (L. plantarum YW11) isolated from Tibetan kefir involves comparison of the complete genome sequences of the isolated strain with other closely related L. plantarum strains.
Tariq Aziz   +9 more
doaj   +1 more source

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