Results 191 to 200 of about 667,306 (306)

High‐Energy‐Density Redox Flow Batteries: Mechanisms, Design Strategies, and Recent Progress

open access: yesChemistry – A European Journal, EarlyView.
ABSTRACT The inherent intermittency of energy sources such as solar and wind power hinders the transition to renewable energy, necessitating advanced energy storage solutions. Enhancing energy density is crucial for lowering system costs and enabling large‐scale deployment.
Xiaolian Zhao   +8 more
wiley   +1 more source

Bayesian Optimization of Solvent‐Free Thermal Amidation via Reactive Extrusion

open access: yesChemistry – A European Journal, EarlyView.
Thermal amidation between a carboxylic acid and an amine was successfully conducted in an extruder in the absence of solvent, coupling agent, or catalyst, relying on an adapted Bayesian Optimization protocol. Active pharmaceutical ingredient moclobemide was synthesized on a larger scale, achieving excellent yield and low Process Mass Intensity (PMI ...
Matthieu Lavayssiere   +2 more
wiley   +1 more source

Self‐Immolative Gels: Programmable Degradation Using Self‐Immolative Linkers and Polymers

open access: yesChemistry – A European Journal, EarlyView.
Self‐immolative linkers and polymers undergo bond‐cleaving reaction cascades in response to specific stimuli. Their incorporation into gels can be harnessed to release cargo, induce property changes, or trigger degradation in a highly controlled manner. These functions can be employed in applications such as sensing and drug delivery.
Chuanfeng Li, Elizabeth R. Gillies
wiley   +1 more source

Tetrazine Ligation in Living Systems: Beyond Fast Kinetics to Effective Bioorthogonality

open access: yesChemistry – A European Journal, EarlyView.
Rapid reaction kinetics (k2) alone do not ensure successful tetrazine ligation in living systems. This review introduces ‘effective orthogonality’—focusing on chemical survival, availability, and encounter—as a practical framework. We highlight how bottlenecks shift from cellular sinks to in vivo delivery limits, offering design strategies for reliable
Junhyeong Yim   +3 more
wiley   +1 more source

Beyond hydrogen: Process design of a biogas steam reformer for Fischer–Tropsch synthesis

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
The effect of pressure and steam to carbon ratio on carbon conversion. Abstract We present an analysis of a pilot‐scale multi‐tubular biogas steam reforming reactor, part of a sustainable aviation fuel (SAF) development project in Brazil. The novelty of this work is the application of a new, validated power law kinetic model, specifically developed for
Rafael Belo Duarte   +3 more
wiley   +1 more source

Financial Toxicity Associated with Biological Medicines: A Scoping Review

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Financial toxicity, defined as the economic burden experienced by patients due to medication and other healthcare costs and their consequences, such as material, psychosocial and behavioral effects, represents a significant concern for individuals receiving biological medicines.
Laura Sara Maria Saarukka   +4 more
wiley   +1 more source

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