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Cell‐based assays in GPCR drug discovery
Biotechnology Journal, 2008AbstractG protein‐coupled receptors (GPCRs) transmit extracellular signals into the intracellular space, and play key roles in the physiological regulation of virtually every cell and tissue. Characteristic for the GPCR superfamily of cell surface receptors are their seven transmembrane‐spanning α‐helices, an extracellular N terminus and intracellular ...
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Cell Based Assays for Drug Screening
1997A CRE-alkaline Phosphatase reporter construct has been introduced into a mammalian cell line to investigate signal transduction pathways used by the calcitonin receptor. Calcitonin activated alkaline Phosphatase production in the CRE-reporter cell line.
Elizabeth Keenan +3 more
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Cell-based assays as an alternative for the study of aquatic toxicity of pharmaceuticals
Environmental science and pollution research international, 2019E. Rodrigues +3 more
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Ubiquitous plant compounds disturb cell-based assays
Journal of Ethnopharmacology, 2011Saaby, Lasse, Jäger, Anna K
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In vitro cell-based assays for evaluation of antioxidant potential of plant-derived products
Free radical research, 2016Luís Cláudio Nascimento da Silva +7 more
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Cell-based assay for monitoring transglutaminase activity
Analytical Biochemistry, 2004Ju-Hong, Jeon +8 more
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Cell-based Assays for Assessing Toxicity: A Basic Guide.
Medicinal chemistry, 2016R. Parboosing +3 more
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