Results 201 to 210 of about 36,354 (283)

Cell-derived microparticle and vascular medicine

Japanese Journal of Thrombosis and Hemostasis, 2011
openaire   +2 more sources

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Sleep deprivation aggravates hepatocytes steatosis and insulin resistance by regulating exosomal microRNAs

Interdisciplinary Medicine, EarlyView.
Sleep deprivation accelerates the progression of MASLD and IR by up‐regulating the expression of miR‐3572‐5p and down‐regulating the expression of miR‐183‐5p in circulating exosomes, thereby inhibiting fatty acid β‐oxidation and disrupting insulin signaling pathways. Abstract Sleep deprivation (SD) threatens human health and increases the prevalence of 
Xinxin Xu, Lulu Li, Ying Cao, Ying Wang, Chao Yang, Alexander Nikolaevich Orekhov, Yuanfeng Lu, Houbin Chu, Chuanrong Zhao, Guixue Wang, Guohua Song   +10 more
wiley   +1 more source

Catabolic effects of endothelial cell-derived microparticles on disc cells: Implications in intervertebral disc neovascularization and degeneration. [PDF]

J Orthop Res, 2016
Pohl PH, Lozito TP, Cuperman T, Yurube T, Moon HJ, Ngo K, Tuan RS, St Croix C, Sowa GA, Rodrigues LM, Kang JD, Vo NV.   +11 more
europepmc   +1 more source

Artificial cell: An emerging bioactive material with advanced applications in cancer theranostics

Interdisciplinary Medicine, EarlyView.
Artificial cells are emerging as attractive biomimetic bioactive materials that recapitulate key structures and functions of natural cells. This review systematically summarizes their major types, versatile fabrication strategies, tuneable properties and programmable biomimetic behaviours, highlights their cutting‐edge integrated applications in cancer
Daikun Wu, Shuo Yang, Hongjing Dou
wiley   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Unveiling the roles of extracellular vesicles in hematologic malignancies: Pathogenesis, diagnostic tools, and clinical translation

Interdisciplinary Medicine, EarlyView.
Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen, Zhiyuan Wu, Feng Zhang, Yuan Meng, Hongyan Liao, Tony Y. Hu   +5 more
wiley   +1 more source

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro, Rosângela Mayer Gonçalves, Marcelle Gomes Pegurier, Isabelle Amorim, Alexandre Malta Rossi, Leandra Santos Baptista   +5 more
wiley   +1 more source

Peri‐implant disease pathogenesis animal models: Consensus report of Workgroup 1 of the IADR Implantology Research Group Best Evidence Consensus Symposium on Peri‐Implant Disease and Its Treatment

Journal of Periodontology, EarlyView.
Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis, Leonardo Mancini, Panos Afouxenides, Andrea Roccuzzo, IADR IRG Peri‐implantitis Best Evidence Consensus Working Group 1, Tara Aghaloo, Georgios Belibasakis, Nagihan Bostanci, Li Dehua, Nikolaos Donos, Alpdogan Kantarci, Alireza Moshaverinia, Flavia Pirih, Mia Rakic, Frank Schwarz, Sukirth Ganesan   +15 more
wiley   +1 more source

Silk–Hyaluronic Acid Laryngoplasty Outcomes: An Independent Tertiary Center Experience

The Laryngoscope, EarlyView.
Silk–hyaluronic acid (silk‐HA) injection laryngoplasty demonstrated favorable voice outcomes for glottic insufficiency in an independent tertiary academic voice center experience. In a within‐patient comparison, silk‐HA showed comparable efficacy to prior HA injection, with 79.3% of patients reporting partial to significant improvement.
Benjamin Wajsberg, Anastasia M. Christ, Sarah E. Benyo, Connor A. Keuchel, Radhika Duggal, Richard Wu, Michael S. Benninger, Rebecca C. Nelson, Paul C. Bryson, William S. Tierney   +9 more
wiley   +1 more source