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Statin and endothelial cell-derived microparticles

Thrombosis and Haemostasis, 2008
Thromb Haemost 2008; 100: 377–378 Microparticles (MP) are small membrane vesicles that are released from many different cell types by a process of exocytic budding of the plasma membrane (1). Because MP disseminate various bioactive effectors originating from the parent cells, they can alter vascular function and may induce biological responses ...
openaire   +2 more sources

The Role of Cell-derived Microparticles in Cardiovascular Diseases: Current Concepts

Current Pharmaceutical Design, 2022
Abstract: Cardiovascular disease remains the main cause of human morbidity and mortality in developed countries. Microparticles (MPs) are small vesicles originating from the cell membrane as a result of various stimuli and particularly of biological processes that constitute the pathophysiology of atherosclerosis, such as endothelial damage. They form
Panagiota K. Stampouloglou   +9 more
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Effect of strenuous physical exercise on circulating cell-derived microparticles

Clinical Hemorheology and Microcirculation, 2011
Strenuous exercise is associated with an inflammatory response involving the activation of several types of blood cells. In order to document the specific activation of these cell types, we studied the effect of three maximal exercise tests conducted to exhaustion on the quantitative and qualitative pattern of circulating cell-derived microparticles ...
Chaar, Vicky   +7 more
openaire   +4 more sources

Potential roles of cell-derived microparticles in ischemic brain disease

Neurological Research, 2009
The objective of this study is to review the role of cell-derived microparticles in ischemic cerebrovascular diseases.An extensive PubMed search of literature pertaining to this study was performed in April 2009 using specific keyword search terms related to cell-derived microparticles and ischemic stroke.
J. Steven Alexander   +7 more
openaire   +3 more sources

Cell-Derived Microparticles Promote Coagulation after Moderate Exercise

Medicine & Science in Sports & Exercise, 2011
Cell-derived procoagulant microparticles (MP) might be able to contribute to exercise-induced changes in blood hemostasis.This study aimed to examine (i) the concentration and procoagulant activity of cell-derived MP after a moderate endurance exercise and (ii) the differences in the release, clearance, and activity of MP before and after exercise ...
Gordon P. Otto   +4 more
openaire   +3 more sources

Endothelial Cell–Derived Microparticles in Allogeneic Hematopoietic Stem Cell Recipients

Transplantation, 2006
BACKGROUND: Alterations of microparticles derived from different cell types are described in a number of diseases associated with inflammation and hemostatic disorders. METHODS: In this prospective study, we firstly analyzed endothelial cell derived microparticles (EMP) in 19 hematopoietic stem cell recipients. Cultured human umbilical vein endothelial
Hans-Jochem Kolb   +7 more
openaire   +3 more sources

Cell-Derived Microparticles and Complement Activation in Preeclampsia Versus Normal Pregnancy

Placenta, 2007
Inflammation plays a major role in the vascular dysfunction seen in preeclampsia, and several studies suggest involvement of the complement system.To investigate whether complement activation on the surface of microparticles is increased in plasma of preeclamptic patients versus healthy pregnant controls.Microparticles from plasma of preeclamptic (n=10)
Auguste Sturk   +6 more
openaire   +4 more sources

Circulating Cell-Derived Microparticles in Thrombotic and Inflammatory Disorders

2005
It is now recognized that all circulating blood cells, as well as endothelial cells (EC), continuously shed small membranous vesicles (microparticles [MPs]), which are approximately less than 1 µm, and that levels of circulating MPs are sensitive indicators of disease activity.
Joaquin J. Jimenez   +4 more
openaire   +2 more sources

Cell-derived microparticles and vascular pregnancy complications: a systematic and comprehensive review

Fertility and Sterility, 2013
To assess current studies on the relationship between cell-derived microparticles (cMP) and recurrent miscarriages (RM) and pre-eclampsia (PE), and review the relationships between cMP and inflammatory and clot pathways, antiphospholipid antibodies (aPL), cytokines, and pregnancy complications.Systematic and comprehensive review of the literature from ...
Carles Palacio-Garcia   +3 more
openaire   +3 more sources

The softness of tumour-cell-derived microparticles regulates their drug-delivery efficiency

Nature Biomedical Engineering, 2019
Qingle Liang   +12 more
semanticscholar   +1 more source

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