Results 71 to 80 of about 29,386 (244)

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme. [PDF]

PLoS ONE, 2013
Cannabinoids, the active components of marijuana and their derivatives, are currently investigated due to their potential therapeutic application for the management of many different diseases, including cancer.
Dolores Hernán Pérez de la Ossa, Mar Lorente, Maria Esther Gil-Alegre, Sofía Torres, Elena García-Taboada, María Del Rosario Aberturas, Jesús Molpeceres, Guillermo Velasco, Ana Isabel Torres-Suárez   +8 more
doaj   +1 more source

All‐Amyloid Functional Coacervates

Advanced Materials, EarlyView.
This study introduces an all‐amyloid interfacial complex coacervate technique that employs charge‐mediated or functionalization‐assisted complexation of oppositely charged food protein‐derived amyloid nanofibrils to engineer functional soft constructs across multiple length scales.
Seyyed Alireza Hashemi, Mohammad Peydayesh, Laura Baraldi, Mohammad Arjmand, Raffaele Mezzenga   +4 more
wiley   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Spheroid‐On‐A‐Drop: A Modular Droplet Microfluidics Platform

Advanced Materials Technologies, EarlyView.
The proposed Spheroid‐on‐a‐Drop platform represents a reproducible and tunable platform for the fabrication of biocompatible GelMA‐based microgels, able to support controlled 3D tumor spheroid culture. Its precise control over droplet dynamics and cell distribution paves the way for advanced applications in tissue modeling, drug screening, and ...
A. Fergola, V. Vighetto, G. Mesiano, A. Cosola, S. L. Marasso, M. Cocuzza, C. F. Pirri, L. Napione, F. Frascella   +8 more
wiley   +1 more source

Tissue Factor-Expressing Tumor-Derived Extracellular Vesicles Activate Quiescent Endothelial Cells via Protease-Activated Receptor-1

Frontiers in Oncology, 2017
Tissue factor (TF)-expressing tumor-derived extracellular vesicles (EVs) can promote metastasis and pre-metastatic niche formation, but the mechanisms by which this occurs remain largely unknown. We hypothesized that generation of activated factor X (FXa)
Sara P. Y. Che, Jeannie Y. Park, Tracy Stokol   +2 more
doaj   +1 more source

Wood‐Derived Nanocellulose‐Biocarbon Fresnel‐Zone Plate Lenses for Sub‐THz Frequency Applications

Advanced Materials Technologies, EarlyView.
Wood‐derived nanocellulose and lignin‐based biocarbon were combined to fabricate fully bio‐based Fresnel zone plate (FZP) lenses for sub‐terahertz frequencies. These sustainable FZP lenses exhibit low dielectric loss and high directivity, achieving performance comparable to that of metallic references, and remain functional under environmental stress ...
Riikka Haataja, Mikko Kokkonen, Niina Halonen, Sami Myllymäki, Umair Rafique, Mandeep Singh, Ossi Laitinen, Heli Jantunen, Kristiina Oksman, Henrikki Liimatainen   +9 more
wiley   +1 more source

Upscaling Pulsed Laser Fragmentation in Liquids by Advanced Free‐Flow Setups

Advanced Materials Technologies, EarlyView.
Advanced flow setups providing thin colloid films are introduced to upscale pulsed laser fragmentation in liquids for sustainable nanoparticle synthesis. Their potential is demonstrated by yielding remarkably small ZnO nanoparticles of <7 nm. Numerical simulations complement the study, revealing that the superior performance can be attributed to ...
Jan Lino Kricke, Zongwen Fu, Sebastian Burgmann, Uwe Janoske, Carlos Doñate‐Buendía, Bilal Gökce   +5 more
wiley   +1 more source

A Superlubricated Magnetically Steerable Microcatheter with Integrated Optical and Fluidic Channels

Advanced Robotics Research, EarlyView.
A magnetically steerable microcatheter with integrated optical and fluidic channels is developed for multifunctional navigation in tortuous anatomical environments. A surface‐grafted hydrogel coating enables low‐friction actuation. The device demonstrates stable light and fluid delivery during magnetic manipulation, offering a compact platform for ...
Yuntian Du, Ruokun He, Luqi Li, Hesheng Wang, Zhuo‐Chen Ma, Bing Han   +5 more
wiley   +1 more source

Integrated Microfluidic Platform for High‐Throughput Generation of Intestinal Organoids in Hydrogel Droplets

Advanced Science
Organoid research offers valuable insights into human biology and disease, but reproducibility and scalability remain significant challenges, particularly for epithelial organoids. Here, we present an integrated microfluidic platform that addresses these
Barbora Lavickova, Hannah Kronabitter, Mar Cervera‐Negueruela, Eylul Ceylan, Laura Benito‐Zarza, Rubén López‐Sandoval, Irineja Cubela, J. Gray Camp, Jose L. Garcia‐Cordero   +8 more
doaj   +1 more source