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Cell-to-Cell Heterogeneity in Trypanosomes

Annual Review of Microbiology, 2021
Recent developments in single-cell and single-molecule techniques have revealed surprising levels of heterogeneity among isogenic cells. These advances have transformed the study of cell-to-cell heterogeneity into a major area of biomedical research, revealing that it can confer essential advantages, such as priming populations of unicellular organisms
Luzak, Vanessa   +3 more
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The Myeloid Cell Compartment—Cell by Cell

Annual Review of Immunology, 2019
Myeloid cells are a major cellular compartment of the immune system comprising monocytes, dendritic cells, tissue macrophages, and granulocytes. Models of cellular ontogeny, activation, differentiation, and tissue-specific functions of myeloid cells have been revisited during the last years with surprising results; for example, most tissue macrophages ...
Baßler, Kevin   +4 more
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VIRUS-CELL AND CELL-CELL FUSION

Annual Review of Cell and Developmental Biology, 1996
▪ Abstract  Significant progress has been made in elucidating the mechanisms of viral membrane fusion proteins; both those that function at low, as well as those that function at neutral, pH. For many viral fusion proteins evidence now suggests that a triggered conformational change that exposes a previously cryptic fusion peptide, along with a ...
L D, Hernandez   +3 more
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The cell biology of cell-in-cell structures

Nature Reviews Molecular Cell Biology, 2008
For decades, authors have described unusual cell structures, referred to as cell-in-cell structures, in which whole cells are found in the cytoplasm of other cells. One well-characterized process that results in the transient appearance of such structures is the engulfment of apoptotic cells by phagocytosis.
Michael, Overholtzer, Joan S, Brugge
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