Results 41 to 50 of about 11,485,087 (317)

Characterization of the Bronchoalveolar Lavage Fluid by Single Cell Gene Expression Analysis in Healthy Dogs: A Promising Technique

Frontiers in Immunology, 2020
Single-cell mRNA-sequencing (scRNA-seq) is a technique which enables unbiased, high throughput and high-resolution transcriptomic analysis of the heterogeneity of cells within a population.
Aline Fastrès, Dimitri Pirottin, Laurence Fievez, Thomas Marichal, Christophe J. Desmet, Fabrice Bureau, Cécile Clercx   +6 more
doaj   +1 more source

Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome

, 2018
Thousands of cis-elements in genomes are predicted to have vital functions. Although conservation, activity in surrogate assays, polymorphisms, and disease mutations provide functional clues, deletion from endogenous loci constitutes the gold-standard ...
Rajendran Sanalkumar, Jin Soo Kim, Chandler Zuo, Yoon-A Kang, Sunduz Keles, Prithvia Devadas, Duk Hyoung Kim, Emery H. Bresnick, Kyle J. Hewitt, Rajalekshmi Prathibha, Kirby D Johnson, Colin N. Dewey   +11 more
core   +1 more source

Largen: A Molecular Regulator of Mammalian Cell Size Control [PDF]

, 2014
Little is known about how mammalian cells maintain cell size homeostasis. We conducted a novel genetic screen to identify cell-size-controlling genes and isolated Largen, the product of a gene (PRR16) that increased cell size upon overexpression in human
Gandin, Valentina, Li, Wanda, Inoue, Satoshi, Itsumi, Momoe, Silvester, Jennifer Liepa, Shahinian, Arda, Wakeham, Andrew, Lapin, Valentina, Mullen, Peter J., Haight, Jillian, Wang, Feng, Mak, Tak W., Yamamoto, Kazuo, Topisirovic, Ivan, McCracken, Susan, Sasaki, Masato, Sonenberg, Nahum, Oo, Yathor D, Elia, Andrew J., Alexandrova, Roumiana, Ikura, Mitsuhiko, Wakutani, Yosuke, Oo, Yathor D.   +22 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Cell–cell and cell–matrix interactions

Molecular Biology of the Cell, 2013
In this year's annual ASCB Meeting Minisymposium on Cell–Cell and Cell–Matrix Interactions, new data were presented on several aspects of the biology of cell adhesions. The role of cell adhesions in cancer was the topic of three of the talks, two of which were focused on identifying how invasion is affected by cell–matrix and cell–cell adhesions ...
openaire   +2 more sources

Single-cell genome-wide association reveals a nonsynonymous variant in ERAP1 confers increased susceptibility to influenza virus [PDF]

, 2022
During pandemics, individuals exhibit differences in risk and clinical outcomes. Here, we developed single-cell high-throughput human in vitro susceptibility testing (scHi-HOST), a method for rapidly identifying genetic variants that confer resistance ...
Ko, Dennis C., Bergstrom, Emma, Brennan, Richard G, Brennan, Richard G., Jack Anderson, Christopher W. Woods, Erica J. Washington, Chiu, Christopher, Harding, Alfred T., Micah T. McClain, McClain, Micah T., Alfred T. Harding, Schott, Benjamin H, Ko, Dennis C, Gregory, Simon G., Zhu, Xinyu, Bourgeois, Jeffrey S, Gregory, Simon G, McClain, Micah T, Emily R. Ko, Heaton, Nicholas S., Dennis C. Ko, Richard G. Brennan, Zoe Gardener, Paterson, Suzanna, Nicholas S. Heaton, Wang, Liuyang, Washington, Erica J., Woods, Christopher W., Liuyang Wang, Heaton, Nicholas S, Benjamin H. Schott, Schott, Benjamin H., Woods, Christopher W, Thomas W. Burke, Anderson, Jack, Christopher Chiu, Bourgeois, Jeffrey S., Suzanna Paterson, Ko, Emily R, Washington, Erika J, Emma Bergstrom, Xinyu Zhu, Harding, Alfred T, Burke, Thomas W., Jeffrey S. Bourgeois, Gardener, Zoe, Ko, Emily R., Burke, Thomas W, Simon G. Gregory   +49 more
core   +1 more source

MAP4K4 inhibition promotes survival of human stem cell derived cardiomyocyte and reduces infarct size in vivo [PDF]

, 2019
Heart disease is a paramount cause of global death and disability. Although cardiomyocyte death plays a causal role and its suppression would be logical, no clinical counter-measures target the responsible intracellular pathways. Therapeutic progress has
Paiva, MA, Michael, LH, Song, W, Kanayaganam, S, Xie, M, Taffet, GE, Harding, SE, Pavanello, L, Aqil, R, Bellahcene, M, Maifosie, E, Jarvis, A, Wang, SC, Tralau-Stewart, C, Habib, J, Perrior, T, Narasimham, P, Fiedler, Lorna, Newton, G, Golforoush, PA, Noseda, M, Sampson, RD, Bellahcene, Mohamed, Tan, T, Fiedler, LR, Golforoush, Pelin, Jenkins, M, Sano, M, Schneider, MD, Entman, ML, Chapman, K, Faust, D, Tan, T-H, Harding, Sian, Noseda, Michela, Sanmugalingam, D, Schneider, Michael, Stuckey, DJ, Yan, R, Maifoshie, E, Narasimhan, P, Low, CMR, Harada, M   +42 more
core   +2 more sources

Digital puzzle: Alternative media for cell learning in middle school

Bio-Inoved: Jurnal Biologi-Inovasi Pendidikan, 2022
Digital-based biology learning media is very suitable for learning in the era of globalization, especially in visualizing abstract material. Students are familiar with puzzle games; variations of digital puzzles are required for visualization cell ...
Munawarah Fauziah Fazrianti Yulinda, Much. Fuad Saifuddin   +1 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Cell–cell and cell–matrix interactions

Molecular Biology of the Cell, 2014
mbc.E13-11-0671 Molecular Biology of the Cell Volume 25 Page 731 MBoC is pleased to publish this summary of the Minisymposium “Cell−Cell/Cell−Matrix Interactions and Intracellular Signaling” held at the American Society for Cell Biology 2013 Annual Meeting, New Orleans, LA, December 15, 2013.
openaire   +2 more sources